scholarly journals Human Papillomavirus and Carcinogenesis in the Upper Aero-Digestive Tract

10.5772/54800 ◽  
2013 ◽  
Author(s):  
Andres Castillo
2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Isabel Cristina Almonacid Urrego ◽  
◽  
Carmen Cecilia Almonacid Urrego ◽  
Sonia Marcela Rosas Arango ◽  
Edith del Carmen Hernández Rojas ◽  
...  

Digestive tract cancers are frequent worldwide, despite efforts to control known predisposing factors, they keep increasing, this fact suggests that human papillomavirus (HPV) may play an important oncogenic role in these pathologies. In order to argue the incidence that HPV has in the genesis of gastrointestinal tract tumors and to determine if it is a possible causal agent, the scientific literature published to date on the subject was reviewed, and was found that 4.5% of all diagnosed cancers correspond to HPV; 12% are extra cervical, 20% esophagus, 31.9% colon adenomas, 43% colorectal adenocarcinoma, and 35% head and neck neoplasms (HNSCC). The types of HPV reported in the digestive tract are 6, 9, 11, 13, 16.18, 20, 24, 25, 30, 33, 51, 54, 57, DL 416, DL 428 and DL 436. Although, the studies show the HPV impact in the oncogenesis and its role as a prognostic marker in some of them, they do not have hard evidence that reveals this relationship, therefore demonstrating its integration would allow clarifying it.


1997 ◽  
Vol 76 (3) ◽  
pp. 271-276 ◽  
Author(s):  
Estela Turazza ◽  
Alicia Lapena ◽  
Osvaldo Sprovieri ◽  
César Pires Torres ◽  
Carlos Gurucharri ◽  
...  

2013 ◽  
Vol 105 (8) ◽  
pp. 536-545 ◽  
Author(s):  
Devasena Anantharaman ◽  
Tarik Gheit ◽  
Tim Waterboer ◽  
Behnoush Abedi-Ardekani ◽  
Christine Carreira ◽  
...  

2021 ◽  
pp. 33-37
Author(s):  
G.V. Reva ◽  
V.E. Tolmachev ◽  
Yu.V. Dynda ◽  
A.R. Kim

1997 ◽  
Vol 76 (4) ◽  
pp. 271-276
Author(s):  
Estela Turazza ◽  
Alicia Lapena ◽  
Osvaldo Sprovieri ◽  
César Pires Torres ◽  
Carlos Gurucharri ◽  
...  

1997 ◽  
Vol 76 (3) ◽  
pp. 271-276
Author(s):  
Estela Turazza ◽  
Alicia Lapena ◽  
Osvaldo Sprovieri ◽  
César Pires Torres ◽  
Carlos Gurucharri ◽  
...  

Author(s):  
Kun Lee ◽  
Jingyi Si ◽  
Ricai Han ◽  
Wei Zhang ◽  
Bingbing Tan ◽  
...  

There are more supports for the view that human papillomavirus (HPV) infection might be an etiological factor in the development of cervical cancer when the association of persistent condylomata is considered. Biopsies from 318 cases with squamous cell carcinoma of uterine cervix, 48 with cervical and vulvar condylomata, 14 with cervical intraepithelial neoplasia (CIN), 34 with chronic cervicitis and 24 normal cervical epithelium were collected from 5 geographic regions of China with different cervical cancer mortalities. All specimens were prepared for Dot blot, Southern blot and in situ DNA-DNA hybridizations by using HPV-11, 16, 18 DNA labelled with 32P and 3H as probes to detect viral homologous sequences in samples. Among them, 32 cases with cervical cancer, 27 with condyloma and 10 normal cervical epitheliums were randomly chosen for comparative EM observation. The results showed that: 1), 192 out of 318 (60.4%) cases of cervical cancer were positive for HPV-16 DNA probe (Table I)


Sign in / Sign up

Export Citation Format

Share Document