scholarly journals Green Approach in Click Chemistry

2018 ◽  
Author(s):  
Sachin P. Shirame ◽  
Raghunath B. Bhosale
Keyword(s):  
Click Chemistry ◽  
Green Approach

Click Chemistry Expedited Radiosynthesis: Sulfur [18F]fluoride Exchange of Aryl Fluorosulfates

2019 ◽  
Author(s):  
Qinheng Zheng ◽  
Hongtao Xu ◽  
Hua Wang ◽  
Wen-Ge Han Du ◽  
Nan Wang ◽  
...  
Keyword(s):  
Click Chemistry ◽  
High Performance ◽  
Isotopic Exchange ◽  
Tumor Imaging ◽  
Radiochemical Yield ◽  
Exchange Method ◽  
Molar Activity ◽  
Positron Emission ◽  
Sulfur Fluoride

The lack of simple, efficient [<sup>18</sup>F]fluorination processes and new target-specific organofluorine probes remains the major challenge of fluorine-18-based positron emission tomography (PET). We report here a fast isotopic exchange method for the radiosynthesis of aryl [<sup>18</sup>F]fluorosulfate based PET agents enabled by the emerging sulfur fluoride exchange (SuFEx) click chemistry. The method has been applied to the fully-automated <sup>18</sup>F-radiolabeling of twenty-five structurally diverse aryl fluorosulfates with excellent radiochemical yield (83–100%) and high molar activity (up to 281 GBq µmol<sup>–1</sup>) at room temperature in 30 seconds. The purification of radiotracers requires no time-consuming high-performance liquid chromatography (HPLC), but rather a simple cartridge filtration. The utility of aryl [<sup>18</sup>F]fluorosulfate is demonstrated by the <i>in vivo</i> tumor imaging by targeting poly(ADP-ribose) polymerase 1 (PARP1).

Conceptual Foundations of Environmental Marketing and Environmental Product

2020 ◽  
Vol 26 (6) ◽  
pp. 665-671
Author(s):  
D. V. Bagnyuk ◽  
A. V. Lebedev
Keyword(s):  
Sustainable Development ◽  
Methodological Approach ◽  
Russian Language ◽  
Future Research ◽  
Environmental Friendliness ◽  
Environmental Marketing ◽  
Qualitative Empirical Research ◽  
Green Approach ◽  
Market Practices ◽  
Conceptual Foundations

The presented study examines the concepts of “environmental marketing” and “environmental product”. The study attempts to conceptualize these terms in Russian language with allowance for the concept of sustainable development and the principles of the circular economy.Aim. The study aims to develop the conceptual foundations of environmental marketing and its derivative — environmental product, laying the groundwork for future research in specifying the concepts of “environmental marketing” and “environmental product”.Tasks. The authors examine the current state of environmental marketing and environmental product in Russia in terms of legislation and market practices; analyze the evolution of these concepts in foreign and Russian publications; systematize experience in this field; provide an original conceptualization of these terms; operationalize their key characteristics and features.Methods. This study is based on qualitative empirical research using such methods as content analysis, synthesis, formalization, and systematization. The theoretical and methodological approach of the study is based on the works of foreign and Russian scientists in the field of environmental marketing, the “green” approach to the promotion of goods, and sustainable enterprise development.Results. A research gap in the conceptualization of “environmental marketing” and “environmental product” in Russian language is identified. The authors provide an original interpretation of these concepts with allowance for the principles of sustainable development and “green” promotion.Conclusions. This study serves to elaborate on the scientific meaning of the concept of “environmental friendliness” applicable in marketing, changing the trend of the increasing number of products that fall under the definition of greenwashing. The published materials can be useful for environmental consultants, marketers, and representatives of legislative authorities in certifying products according to environmental standards.

Use of Click-Chemistry in the Development of Peptidomimetic Enzyme Inhibitors

2014 ◽  
Vol 21 (13) ◽  
pp. 1467-1477 ◽  
Author(s):  
P. Fabbrizzi ◽  
G. Menchi ◽  
A. Guarna ◽  
A. Trabocchi
Keyword(s):  
Click Chemistry ◽  
Enzyme Inhibitors

Synthesis of Porphyrin, Chlorin and Phthalocyanine Derivatives by Azide-Alkyne Click Chemistry

2015 ◽  
Vol 22 (28) ◽  
pp. 3217-3254 ◽  
Author(s):  
Samir Acherar ◽  
Ludovic Colombeau ◽  
Celine Frochot ◽  
Regis Vanderesse
Keyword(s):  
Click Chemistry

Click Chemistry, A Potent Tool in Medicinal Sciences

2015 ◽  
Vol 22 (17) ◽  
pp. 2022-2050 ◽  
Author(s):  
F. Musumeci ◽  
S. Schenone ◽  
A. Desogus ◽  
E. Nieddu ◽  
D. Deodato ◽  
...  
Keyword(s):  
Click Chemistry
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