A case of paraganglioma of the retroperitoneum with intranuclear cytoplasmic inclusions in the giant tumor cells

2020 ◽  
Vol 59 (3) ◽  
pp. 147-151
Author(s):  
Ayano MIZUNO ◽  
Kousei KINOSHITA ◽  
Katsumi KITO ◽  
Atsurou SUGITA ◽  
Toshiharu MAEDA

1999 ◽  
Vol 21 (6) ◽  
pp. 435-436 ◽  
Author(s):  
Maria Sironi ◽  
Rossella Claren ◽  
Maria Santangelo ◽  
Maurizio Spinelli




2004 ◽  
Vol 128 (6) ◽  
pp. 686-688
Author(s):  
Jared J. Abbott ◽  
Robin H. Amirkhan ◽  
Mai P. Hoang

Abstract Malignant melanoma is known to display tremendous histologic diversity. One rare variant is the rhabdoid phenotype, so called because of the appearance of cells resembling rhabdomyoblasts seen in malignant rhabdoid tumors of the kidney. We present the histologic, immunohistochemical, and ultrastructural features of a malignant melanoma composed entirely of rhabdoid cells. A 62-year-old man presented with a 6.5-cm lung mass. Although presumed to be a metastatic lesion, extensive workup failed to reveal a primary tumor site. Histologic sections showed a mass composed entirely of polygonal neoplastic cells with prominent nucleoli and large hyaline cytoplasmic inclusions. The tumor cells were strongly immunoreactive with S100 protein, vimentin, and CD56, and were focally reactive with Mart-1. Tumor cells were negative for Melan-A, tyrosinase, HMB-45, AE1/AE3, cytokeratin (CK) 7, CK8/ 18, CK20, CK903, CAM 5.2, epithelial membrane antigen, smooth muscle actin, desmin, leukocyte common antigen, Bcl-2, CD3, CD20, CD30, CD138, κ and λ light chains, CD68, CD34, factor VIII, synaptophysin, and glial fibrillary acidic protein. Electron microscopy showed cytoplasmic whorls of intermediate filaments containing entrapped rough endoplasmic reticulum, mitochondria, and lipid. Recognition of this rare variant of malignant melanoma is important in the evaluation of tumors with rhabdoid morphology.



1998 ◽  
Vol 18 (6) ◽  
pp. 475-476 ◽  
Author(s):  
Tadao K. Kobayashi ◽  
Makoto Katoh ◽  
Shinsuke Watanabe ◽  
Chiyuki Kaneko


2008 ◽  
Vol 36 (7) ◽  
pp. 531-533 ◽  
Author(s):  
Chiyuki Kaneko ◽  
Kazuo Kato ◽  
Tadao K. Kobayashi ◽  
Hirofumi Sakamoto


Endocrine ◽  
2013 ◽  
Vol 46 (1) ◽  
pp. 114-122
Author(s):  
Salvatore Arena ◽  
Adele Latina ◽  
Michele Stornello ◽  
Giovanna Saraceno ◽  
Salvatore Benvenga


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