scholarly journals Bipolar Electrochemical Fluorination of Triphenylmethane and Bis(phenylthio)diphenylmethane Derivatives in a U-shaped Cell

2021 ◽  
Author(s):  
Naoki SHIDA ◽  
Elena VILLANI ◽  
Mokurai SANUKI ◽  
Kazuhiro MIYAMOTO ◽  
Akihiro GOTOU ◽  
...  
Keyword(s):  
Electrochemical Fluorination ◽  
Shaped Cell

scholarly journals Flow Electrochemistry: A Safe Tool for Fluorine Chemistry

2021 ◽  
Author(s):  
Bethan Winterson ◽  
Tim Rennigholtz ◽  
Thomas Wirth
Keyword(s):  
Fluorine Chemistry ◽  
Electrochemical Fluorination

The heightened activity of compounds containing fluorine, especially in the field of pharmaceuticals, provides major impetus for the development of new fluorination procedures. A scalable, versatile, and safe electrochemical fluorination...

The electrochemical fluorination of propene

1976 ◽  
Vol 6 (1) ◽  
pp. 23-32 ◽  
Author(s):  
F. G. Drakesmith ◽  
D. A. Hughes
Keyword(s):  
Electrochemical Fluorination

A New Technology for Three-Dimensional Cell Culture: The Hydrodynamic Focusing Bioreactor

1999 ◽  
Author(s):  
Yow-Min D. Tsao ◽  
Steve R. Gonda
Keyword(s):  
Cell Culture ◽  
New Technology ◽  
Three Dimensional ◽  
Culture Vessel ◽  
Air Bubbles ◽  
Hydrodynamic Focusing ◽  
Shaped Cell ◽  
Fluid Environment ◽  
Dimensional Cell ◽  
Low Shear

Abstract The Hydrodynamic Focusing Bioreactor (HDFB) developed by NASA at the Johnson Space Center provides a unique hydrofocusing capability that simultaneously enables a low-shear culture environment and a unique hydrofocusing-based “herding” of suspended cells, cell aggregates, and air bubbles. The HDFB is a rotating dome-shaped cell culture vessel with a centrally located sampling port and an internal rotating viscous spinner attached to a rotating base. The vessel and viscous spinner can rotate at different speeds and in either the same or different directions. Adjusting the differential rotation rate between the vessel and spinner results in a controllable hydrodynamic focusing force. The resultant hydrodynamic force suspends the cells in a low-shear fluid environment that supports the formation of delicate three-dimensional tissue assemblies. Both suspension and anchorage-dependent cells have been successfully cultured.

scholarly journals Highly selective electrochemical fluorination of dithioacetal derivatives bearing electron-withdrawing substituents at the position α to the sulfur atom using poly(HF) salts

2015 ◽  
Vol 11 ◽  
pp. 85-91 ◽  
Author(s):  
Bin Yin ◽  
Shinsuke Inagi ◽  
Toshio Fuchigami
Keyword(s):  
Sulfur Atom ◽  
Nitrile Group ◽  
Amide Group ◽  
Sharp Contrast ◽  
Product Selectivity ◽  
Electrochemical Fluorination ◽  
Weak Electron ◽  
Electron Withdrawing Substituents

Anodic fluorination of dithioacetals bearing electron-withdrawing ester, acetyl, amide, and nitrile groups at their α-positions was comparatively studied using various supporting poly(HF) salts like Et3N·nHF (n = 3–5) and Et4NF·nHF (n = 3–5). In the former two cases, the corresponding α-fluorination products or fluorodesulfurization products were obtained selectively depending on supporting poly(HF) salts used. In sharp contrast, in the latter two cases, fluorination product selectivity was strongly affected by the electron-withdrawing ability of α-substituents: A dithioacetal bearing a relatively weak electron-withdrawing amide group provided a fluorodesulfurization product selectively while a dithioacetal having a strongly electron-withdrawing nitrile group gave the α-fluorination product predominantly regardless of the poly(HF) salts used.

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