scholarly journals Primary Yolk Sac Tumor of the Endometrium with MRI Findings: A Case Report

2020 ◽  
Vol 17 (4) ◽  
Author(s):  
Dalin Zhu ◽  
Fan Feng ◽  
Meijuan Peng
Keyword(s):  
English Literature ◽  
Lower Abdominal Pain ◽  
Side Wall ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Mri Findings ◽  
Adc Value ◽  
Gynecology And Obstetrics ◽  
Mri Scans ◽  
The Right

: Primary yolk sac tumor (YST) of the endometrium is a very rare malignant germ cell tumor, primary YST of the endometrium with detailed magnetic resonance imaging (MRI) and contrast-enhanced MRI (CE-MRI) findings have not yet been reported in the English literature. We report a 40-year-old woman presenting with irregular lower abdominal pain and dysmenorrhea for more than 5 months. MRI showed a lesion in the right side wall of the uterus. Postoperative pathology and immunohistochemistry confirmed the diagnosis of primary YST of the endometrium with the International Federation of Gynecology and Obstetrics (FIGO) system staging of IV. The signal of the tumor was complex and lacked specific characteristic. Diffusion-weighted imaging (DWI) showed that the lesion is diffuse limited, the average apparent diffusion coefficient (ADC) value of the solid component was 0.735 × 10-3 mm2/s. CE-MRI showed that the irregular lesions presented uneven and mild enhancement in the arterial stage, and continued to strengthen in the venous phase, and strengthened close to the myometrium in the delayed phase. Primary YST of the endometrium should be considered if MRI scans show an irregular lesion in the myometrium with high level of alpha-fetoprotein (AFP).

scholarly journals Ultrasound case of the day. Endodermal sinus tumor (yolk sac tumor) of the right ovary.

Radiographics ◽  
1986 ◽  
Vol 6 (4) ◽  
pp. 734-737
Author(s):  
M A Sandler ◽  
R Walter ◽  
G H Beute ◽  
A H Haggar ◽  
B L Madrazo ◽  
...  
Keyword(s):  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Endodermal Sinus Tumor ◽  
The Right ◽  
Sinus Tumor

scholarly journals A Case Report of Yolk Sac Tumor in Cerebellar Hemisphere and Review of Literature

2020 ◽  
Author(s):  
Yuting Zhang ◽  
Lusheng Li ◽  
Ling He
Keyword(s):  
Case Report ◽  
Histopathological Examination ◽  
Case Reports ◽  
Yolk Sac ◽  
Alpha Fetoprotein ◽  
Yolk Sac Tumor ◽  
Cerebellar Hemisphere ◽  
Review Of Literature ◽  
Intracranial Germ Cell Tumor ◽  
The Right

Abstract Background: Yolk sac tumor also known as endodermal sinus tumor, is a rare intracranial germ cell tumor. We reported a case of yolk sac tumor in cerebellar hemisphere, and reviewed associated literatures. The majority of tumor locations are near the midline. On review of literature, very few case reports of intracranial yolk sac tumor have been published, and there is only one case report has described a yolk sac tumor arising from the cerebellum. Case presentation: A two years old boy admitted to our hospital due to headache and unsteady gait for six days. CT and MRI demonstrated a tumor in the right cerebellar hemisphere, and the blood and cerebrospinal fluid alpha-fetoprotein were found increased. It was diagnosed as yolk sac tumor after operation comfirmed by histopathological examination. Postoperative chemotherapy was performed, and the patient suffered no tumor recurrence one year and a half after the surgery. Conclusions: The clinical characteristics and imaging diagnosis of intracranial yolk sac tumor are lack of specificity, the comfirmed diagnosis is depending on the combination of elevated alpha-fetoprotein and histopathological examination.

scholarly journals Combined hepatoblastoma and yolk sac tumor of the liver

2020 ◽  
Vol 19 (1) ◽  
pp. 92-99
Author(s):  
M. M. Morozova ◽  
A. V. Varlamov ◽  
O. V. Dolzhansky ◽  
A. V. Filin ◽  
D. S. Burmistrov ◽  
...  
Keyword(s):  
Morphological Structure ◽  
Personal Data ◽  
Yolk Sac ◽  
Alpha Fetoprotein ◽  
Yolk Sac Tumor ◽  
Histological Structure ◽  
Beta Catenin ◽  
Right Lobe ◽  
Mitotic Figures ◽  
The Right

A 6-year-old patient was admitted to the Petrovsky National Research Center of Surgery in Moscow, diagnosed with hepatoblastoma (HB) of the right lobe of the liver and after undergoing 4 cycles of SIOPEL (super PLADO) pre-operative chemotherapy. An immunohistochemistry test, performed after liver resection, revealed a rare combination of mixed epithelial and mesenchymal hepatoblastoma and yolk sac tumor. The epithelial component of HB consisted of highly differentiated fetal cells, while the mesenchymal component consisted of osteoid. The morphological structure of the second lesion corresponded to yolk sac tumor. Both tumors had regressive changes conditioned by chemotherapy: these changes were most pronounced in HB. In the highly differentiated fetal component of HB it was possible to detect a weak focal perinuclear alpha-fetoprotein expression, HepPar expression, membranous expression of beta-catenin and diffuse glutamine synthetase expression. Mitotic figures were not determined. The node of the yolk sac tumor had the characteristic histological structure of an endodermal sinus tumor with a hepatoid component. In the main tumor node and its nodular elements in the fibrovascular stroma it was possible to identify alpha-fetoprotein expression, CD34, nuclear and cytoplasmic expression of beta-catenin, CDX2, as well as a rare expression of PLAP and multi-cytokeratin, and mitotic activity was high (21 in 10 high power fields, 400x magnification). In the existing literature available to us, there is only one observation of combined hepatoblastoma and yolk sac tumor. Parents patients agreed to use personal data, including the fotos, in research and publications.

scholarly journals Primitive ovarian carcinosarcoma: a clinical and radiological analysis of five cases

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Qiong Xu ◽  
Xiaofei Zhang ◽  
Yu Zou
Keyword(s):  
Careful Analysis ◽  
Cystic Mass ◽  
Ca 125 ◽  
Transverse Diameter ◽  
Imaging Features ◽  
Imaging Findings ◽  
Adc Value ◽  
Pathologic Evaluation ◽  
Mri Scans ◽  
The Right

Abstract Background Ovarian carcinosarcomas (OCS) are very rare tumors composed of a mixture of carcinomatous and sarcomatous elements. There have been only scattered case studies that have described the imaging findings. In order to improve the awareness of this rare tumor, this study aimed to analyze the clinical and imaging features of five cases of OCS confirmed by surgical pathologic evaluation. Methods This retrospective study includes five OCS patients diagnosed and treated at our institute. The clinical course and imaging findings of all patients were retrospectively analyzed. The patients were 31 to 59 years of age. All five patients underwent CT scans, two underwent MRI scans. Results The five patients have no specific symptoms. Four patients had elevated CA 125 levels and three patients had elevated CA 153 levels. All patients had unilateral tumors, four in the left ovary, one in the right ovary. The largest transverse diameter of the tumors ranged from 11 cm to 14 cm. Two tumors showed solid masses with unequally sized cystic areas or necrosis, one showed a multilocular cystic mass with a large solid protrusion, two tumors showed a larger cystic mass with multiple mural nodules. The solid components of the tumors demonstrated restricted diffusion (the average ADC value being 998 mm2/s and 1102 mm2/s, respectively), and showed moderate or obvious enhancement. All five patients were treated by surgical resection and adjuvant chemotherapy. One patient is currently undergoing post-operative chemotherapy 1 month after operation and clinical stable. Three patients survived and showed no obvious recurrence and / or metastasis in follow-up from 9 to 59 months. One patient died from recurrence and metastasis. Conclusions OCS are rare and demonstrate variable CT and MRI morphological appearances. Due to the heterogeneous nature and very low morbidity of OCS, combination of careful analysis of imaging findings and clinical features might be useful for a more accurate diagnosis of OCS.

scholarly journals Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult

2012 ◽  
Vol 2012 ◽  
pp. 1-5
Author(s):  
Toshihide Takahashi ◽  
Eiichi Ishikawa ◽  
Yosuke Masuda ◽  
Tetsuya Yamamoto ◽  
Taiki Sato ◽  
...  
Keyword(s):  
Germ Cell ◽  
Frontal Lobe ◽  
Germ Cell Tumor ◽  
Germ Cell Tumors ◽  
Yolk Sac ◽  
Cell Tumor ◽  
Yolk Sac Tumor ◽  
Mri Findings ◽  
Mixed Germ Cell Tumor ◽  
Subtotal Removal

Intracranial nongerminomatous germ cell tumors (NGGCTs) in unusual locations are extremely rare. Here, we report a case of a yolk sac tumor in the frontal lobe in a middle-aged patient. A 42-year-old man was admitted to our hospital for headache and nausea. Magnetic resonance imaging (MRI) showed an enhanced mass lesion with a marked cyst component. The serum alpha-fetoprotein (αFP) level was extremely high. Histological examination of specimens after subtotal removal revealed a primary mixed germ cell tumor with extensive yolk sac tumor elements, often referred to as an intracranial “yolk sac tumor.” The preoperative diagnosis of NGGCTs in unusual age and locations is extremely difficult. Clinicians should consider the possibility of NGGCTs, including yolk sac tumors, when intracranial tumors with unusual MRI findings are encountered.

Pure Yolk-Sac Tumor of the Lung

2008 ◽  
Vol 16 (5) ◽  
pp. 410-411 ◽  
Author(s):  
Ahmet Basoglu ◽  
Aysen T Sengul ◽  
Yasemin B Buyukkarabacak ◽  
Tulin D Yetim ◽  
Levent Yildiz
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumors ◽  
Middle Lobe ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
The Right

Primary germ cell tumors of the chest often localize in the anterior mediastinal compartment. Such tumors originating from lungs and pleura are rare. Chest tomography revealed a mass in the middle lobe of the right lung in a 25-year-old man. A middle lobe medial segmentectomy was performed, and chemotherapy was applied postoperatively.

scholarly journals Liver metastasis from an ovarian Yolk-Sac-Tumor: A case report and review of the literature

2021 ◽  
pp. 071-074
Author(s):  
Ezzahra Aboutarik Fatima ◽  
Maroua Michouar ◽  
Adil Ait Errami ◽  
Sofia Oubaha ◽  
Zouhour Samlani ◽  
...  
Keyword(s):  
Ovarian Tumor ◽  
Abdominal Mass ◽  
Stage Iv ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Endodermal Sinus Tumor ◽  
Abdominal Magnetic Resonance Imaging ◽  
The Right ◽  
Sinus Tumor ◽  
Immunohistological Study

The endodermal sinus tumor or Yolk sac tumor is a rare ovarian tumor that classically occurs in adolescents and young women, it is a histological type rarely found in clinical practice. We report the case of a 24-year-old woman presenting with an ovarian tumor of the endodermal sinus with hepatic metastasis revealed by a painful abdominal mass in the right hypochondrium associated with a deterioration of the general condition. The blood Alpha-Fetoprotein (AFP) level was 71,300 ng / ml. Abdominal magnetic resonance imaging revealed multiple liver nodules and masses, associated with a magma of secondary lymphadenopathy. The immunohistological study of the hepatic puncture biopsy allowed the diagnosis of a hepatic localization of an ovarian endodermal sinus tumor (Yolk-Sac-Tumor). The tumor was classified stage IV-B of the FIGO 2014 classification, which does not allow a curative approach. Chemotherapy treatment (BEP protocol) was started.

scholarly journals Huge hemorrhagic ovarian cyst alongside suspected ovarian torsion: a case report

2020 ◽  
Vol 7 (2) ◽  
pp. 91-94
Author(s):  
Namita Sindan ◽  
Adheesh Bhandari
Keyword(s):  
Ovarian Cyst ◽  
Ovarian Tissue ◽  
Lower Abdominal Pain ◽  
Ovarian Torsion ◽  
Reproductive Age ◽  
Ovarian Cysts ◽  
Gynecology And Obstetrics ◽  
The Right ◽  
Reproductive Age Group

An ovarian cyst is usually a relatively large, fluid-filled cystic structure (diameter greater than 3 cm) that originates from the surface or inside the ovary. Ovarian cysts can be simple or complex, depending on their internal material. Hemorrhagic ovarian cysts (HOCs) are commonly seen in clinical practice. Most of them resolve naturally during follow-up except in a minority of cases in which surgical intervention is needed. Ovarian torsion indicates partial or complete rotation of the ovary and a portion of the fallopian tube along its supplying vascular pedicle. It usually occurs in the reproductive age group, more on the right side (about 60%), and often presents with acute lower abdominal pain lasting for a few hours to 24 hours. It is one of the harmful conditions, hampering blood supply of ovary which may rise to overall necrosis of ovarian tissue and other difficulties, if not identified and managed in time. We present a case of a huge hemorrhagic ovarian cyst managed in the Department of Gynecology and Obstetrics, Paropakar Maternity and Women’s Hospital, Kathmandu, Nepal.

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