Inhibitory Effects of Brazilian Propolis on Tumor Promotion in Two-Stage Mouse Skin Carcinogenesis

2012 ◽  
Author(s):  
Yasukawa
Keyword(s):  
Mouse Skin ◽  
Tumor Promotion ◽  
Skin Carcinogenesis ◽  
Inhibitory Effects ◽  
Two Stage ◽  
Brazilian Propolis

Inhibitory Effects of Lanostane-Type Triterpene Acids, the Components of Poria cocos, on Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate in Two-Stage Carcinogenesis in Mouse Skin

Oncology ◽  
1996 ◽  
Vol 53 (5) ◽  
pp. 382-385 ◽  
Author(s):  
Tomohiro Kaminaga ◽  
Ken Yasukawa ◽  
Hiroshi Kanno ◽  
Takaaki Tai ◽  
Yoshiki Nunoura ◽  
...  
Keyword(s):  
Mouse Skin ◽  
Tumor Promotion ◽  
Inhibitory Effects ◽  
Two Stage ◽  
Poria Cocos ◽  
Triterpene Acids

scholarly journals Inhibitory Effects of Gymnema (Gymnema sylvestre) Leaves on Tumour Promotion in Two-Stage Mouse Skin Carcinogenesis

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Ken Yasukawa ◽  
Sakiko Okuda ◽  
Yasuhito Nobushi
Keyword(s):  
Mouse Skin ◽  
Ethanol Extract ◽  
Skin Carcinogenesis ◽  
Gymnema Sylvestre ◽  
Active Fraction ◽  
Inhibitory Effects ◽  
Two Stage ◽  
Tumour Promotion ◽  
Ethanol Extracts

Ethanol extracts of gymnema (Gymnema sylvestre) leaves exhibited marked antitumour-promoting activity in anin vivotwo-stage carcinogenesis test in mice using 7,12-dimethylbenz[a]anthracene as an initiator and 12-O-tetradecanoylphorbol-13-acetate (TPA) as a promoter. From the active fraction of the ethanol extract of the gymnema leaves, three triterpenoids were isolated and identified. These compounds were evaluated for their inhibitory effects on TPA-induced inflammation (1 µg/ear) in mice. The tested compounds showed marked anti-inflammatory effects, with a 50% inhibitory dose of 50–555 nmol/ear.

Bisbenzylisoquinoline Alkaloids Inhibit Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate in Two-Stage Carcinogenesis in Mouse Skin

Oncology ◽  
1993 ◽  
Vol 50 (2) ◽  
pp. 137-140 ◽  
Author(s):  
Ken Yasukawa ◽  
Michinori Akasu ◽  
Mieko Takeuchi ◽  
Michio Takido
Keyword(s):  
Mouse Skin ◽  
Tumor Promotion ◽  
Two Stage ◽  
Bisbenzylisoquinoline Alkaloids

Palytoxin is a non-12-O-tetradecanoylphorbol-13-acetate type tumor promoter in two-stage mouse skin carcinogenesis

1986 ◽  
Vol 7 (5) ◽  
pp. 707-710 ◽  
Author(s):  
Hirota Fujiki ◽  
Masami Suganuma ◽  
Michie Nakayasu ◽  
Hiromi Hakii ◽  
Takahiko Horiuchi ◽  
...  
Keyword(s):  
Mouse Skin ◽  
Skin Carcinogenesis ◽  
Tumor Promoter ◽  
Two Stage
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