Inferior Vena Cava Tumour Thrombus from Nonseminomatous Germ Cell Tumour Detected with F-18 FDG PET/CT

Author(s):  
Kearney
2005 ◽  
Vol 28 (2) ◽  
pp. 98-100 ◽  
Author(s):  
Jasmin Katrin Badawi ◽  
Thomas Kittner ◽  
Andreas Manseck ◽  
Manfred WirthaManfred Wirth

2017 ◽  
Vol 42 (7) ◽  
pp. 558-559 ◽  
Author(s):  
Zhanli Fu ◽  
Meng Liu ◽  
Ziao Li ◽  
Jin Zhang ◽  
Qian Li

2020 ◽  
Author(s):  
Chunjuan Jiang ◽  
Guang Ma ◽  
Qiufang Liu ◽  
Shaoli Song

Abstract Background: Microvascular invasion (MVI) is very important in the evaluation of hepatocellular carcinoma (HCC),but diagnosis is determined by postoperative pathology; thus, preoperative non-invasive methods will play an active role. The purpose of this study was to assess the performance of metabolic parameters of preoperative 18F-fluorodeoxyglucose positron emission tomography/computerized tomography (18F-FDG PET/CT) in the prediction of MVI and postoperative recurrence in primary hepatocellular carcinoma.Methods: We retrospectively collected 72 patients with HCC who have performed 18F-FDG PET/CT scan before partial hepatectomy between 2016 and 2019. We used both normal liver tissue and inferior vena cava as the reference background, and combined with clinicopathological features, 18F-FDG PET/CT metabolic and volumetric indices to predict MVI and postoperative recurrence of primary HCC before surgery.Results: Twenty-one of the 72 patients recurred, in recurrent cases showed higher maximum standard uptake value (SUVmax), TNR (ratio of tumor SUVmax to mean SUV [SUVmean] of the background tissue), metabolic tumor volume (MTV) and total lesion glycolysis (TLG) than nonrecurrence cases(p<0.001). All 18F-FDG PET metabolic and volumetric indices for predicting postoperative HCC recurrence were significant on receiver-operating-characteristic (ROC) curve analyses (p<0.05). TNRIVC, TNRNL, MTV, TLGIVC, and TLGNL were significant factors for predicting MVI in HCC (p<0.05). On multivariate analyses, MVI, SUVmax, TNRIVC, TNRNL, MTV, TLGIVC, and TLGNL(p<0.05) are independent risk factors for predicting postoperative HCC recurrence. TNRIVC is the most relevant PET/CT parameter for predicting MVI in HCC, and MTV is the most valuable for predicting postoperative HCC recurrence. Moreover, the PET/CT parameters are more accurate for prognosis with inferior vena cava as a reference background than with normal liver tissue.Conclusion: 18F-FDG PET/CT metabolic and volumetric indices are effective predictors, and could non-invasively provide more comprehensive predictive information on MVI and postoperative recurrence of primary HCC before surgery.


2020 ◽  
Vol 46 (2) ◽  
pp. 153-155
Author(s):  
Sijuan Zou ◽  
Jianyuan Zhou ◽  
Ming Tang ◽  
Ziqing Wang ◽  
Xiaohua Zhu

2020 ◽  
Vol 13 (11) ◽  
pp. e237481
Author(s):  
Peter de Souza ◽  
Chun Wah So ◽  
Deepak Batura ◽  
Wade Gayed ◽  
Eirini Vrentzou

Germ cell tumours (GCT) are the most common testicular neoplasms, seen mainly in young adults. Rarely they can affect extragonadal tissues, either as primary tumours or as metastases, most commonly to retroperitoneal lymph nodes. A ‘burned-out’ testicular tumour is a metastatic GCT with a relatively occult primary testicular tumour, which has histologically spontaneously regressed. We report a case of a 26-year-old man who presented with an acute history of lower back pain and leg swelling. CT demonstrated a large retroperitoneal soft tissue mass causing right-sided hydronephrosis with inferior vena cava and iliofemoral vein thrombosis. Although clinical examination of the testis was normal, ultrasound imaging of the scrotum identified a burned-out testicular primary. Orchiectomy confirmed the diagnosis and the patient responded well to chemotherapy, with no viable residual tumour on follow-up imaging. However, despite nephrostomy insertion, a dimercaptosuccinic acid (DMSA) scan demonstrated loss of function of the right kidney after treatment.


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