Progress of the Research on the Lewis/Brønsted Acid-Catalyzed Nucleophilic Substitution of Propargyl Alcohols

2016 ◽  
Vol 36 (6) ◽  
pp. 1287 ◽  
Author(s):  
Xiaoxiang Zhang ◽  
Chang Lü ◽  
Ping Li ◽  
Bo Fu ◽  
Weiwei Yao
Keyword(s):  
Nucleophilic Substitution ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Brönsted Acid ◽  
Acid Catalyzed ◽  
Propargyl Alcohols

Brønsted Acid-Catalyzed Nucleophilic Substitution of Alcohols

2006 ◽  
Vol 348 (14) ◽  
pp. 1841-1845 ◽  
Author(s):  
Roberto Sanz ◽  
Alberto Martínez ◽  
Delia Miguel ◽  
Julia M. Álvarez-Gutiérrez ◽  
Félix Rodríguez
Keyword(s):  
Nucleophilic Substitution ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Brönsted Acid ◽  
Acid Catalyzed

Brønsted Acid Catalyzed Dehydrative Nucleophilic Substitution of C3-Substituted 2-Indolylmethanols with Azlactones

Synthesis ◽  
2017 ◽  
Vol 50 (02) ◽  
pp. 295-302 ◽  
Author(s):  
Guang-Jian Mei ◽  
Feng Shi ◽  
Chen-Yu Bian ◽  
Dan Li ◽  
Qian Shi
Keyword(s):  
Nucleophilic Substitution ◽  
Substitution Reaction ◽  
Direct Synthesis ◽  
Indole Derivatives ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Whole Process ◽  
Brönsted Acid ◽  
New Strategy ◽  
Acid Catalyzed

An efficient dehydrative nucleophilic substitution reaction of C3-substituted2-indolylmethanols with azlactones has been established. In the whole process, Brønsted acid was supposed to activate two substrates simultaneously. A series of structurally diversified indole derivatives were obtained in generally good yields and high diastereoselectivities (up to 86% yield, >95:5 dr). This protocol not only provides a new strategy for the direct synthesis of structurally diversified indole derivatives, but also enriches the chemistry of 2-indolylmethanols via dehydrative substitution reaction.

Synthetic Scope of Brønsted Acid-Catalyzed Reactions of Carbonyl Compounds and Ethyl Diazoacetate

2021 ◽  
Author(s):  
Mizzanoor Rahaman ◽  
M. Shahnawaz Ali ◽  
Khorshada Jahan ◽  
Damon Hinz ◽  
Jawad Bin Belayet ◽  
...  
Keyword(s):  
Carbonyl Compounds ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Ethyl Diazoacetate ◽  
Brönsted Acid ◽  
Acid Catalyzed ◽  
Catalyzed Reactions

Brønsted Acid-Catalyzed Friedel-Crafts-type Alkylation of Arenes with αAryl Diazoacetates

2021 ◽  
pp. 152751
Author(s):  
Wenming Chen ◽  
Guifang Chen ◽  
Biao Wang ◽  
Wei Wang ◽  
Wei Huang ◽  
...  
Keyword(s):  
Bronsted Acid ◽  
Brønsted Acid ◽  
Brönsted Acid ◽  
Acid Catalyzed
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