Introduction. The diagnosis of sarcoidosis can be established when there is a
compatible clinical-radiological picture together with pathohistological
evidence of noncaseating epitheloid cell granulomas. Novelties in Diagnosis
of Sarcoidosis. Pathohistological specimens can be obtained by conventional
bronchoscopy with endobronchial and transbronchial lung biopsy,
bronchoalveolar lavage, surgical procedures like cervical mediastinoscopy,
diagnostic thoracotomy, video-assisted thoracoscopic surgery, and recently
introduced endoscopic ultrasound techniques (endoscopic ultrasound-guided
fine-needle aspiration and endobronchial ultrasound-guided transbronchial
needle aspiration). Endobronchial ultrasound-guided transbronchial needle
aspiration and endoscopic ultrasound-guided fine-needle aspiration have given
a great contribution to diagnosis of sarcoidosis and present next diagnostic
step after negative bronchoscopy. Conclusion. Reduction of surgical
procedures in diagnosis of sarcoidosis, can be expected (first of all
mediastinoscopy) by introducing endobronchial ultrasound-guided
transbronchial needle aspiration and endoscopic ultrasound-guided fine-needle
aspiration.
Endobronchial ultrasound-guided transbronchial needle aspiration combined with either endoscopic ultrasound-guided fine-needle aspiration or endoscopic ultrasound using the EBUS scope-guided fine-needle aspiration for diagnosing and staging mediastinal diseases: a systematic review and meta-analysis
