A Xanthine-Derivative K+-Channel Opener Protects against Serotonin-Induced Cardiomyocyte Hypertrophy via the Modulation of Protein Kinases

International Journal of Biological Sciences ◽

10.7150/ijbs.7894 ◽

2014 ◽

Vol 10 (1) ◽

pp. 64-72 ◽

Author(s):

Hsuan-Fu Kuo ◽

Yan-Jie Lai ◽

Jung-Chou Wu ◽

Kun-Tai Lee ◽

Chih-Sheng Chu ◽

...

Keyword(s):

Protein Kinases ◽

Cardiomyocyte Hypertrophy ◽

K Channel ◽

Xanthine Derivative ◽

Channel Opener ◽

K Channel Opener

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Evidence of Pharmacologic Preconditioning During PTCA by Intravenous Pre-treatment of ATP-sensitive K+ Channel Opener NICORANDIL

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(97)87992-2 ◽

1998 ◽

Vol 31 (2) ◽

pp. 458A

Author(s):

H Matsuo

Keyword(s):

K Channel ◽

Channel Opener ◽

Pre Treatment ◽

K Channel Opener

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Faculty Opinions recommendation of Characterization of a novel ATP-sensitive K+ channel opener, A-251179, on urinary bladder relaxation and cystometric parameters.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1086152.539136 ◽

2007 ◽

Author(s):

Rodolfo Testa

Keyword(s):

Urinary Bladder ◽

K Channel ◽

Channel Opener ◽

K Channel Opener

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Levcromakalim (K+ channel opener) prevents glyburidc (KATP channel inhibitor)-induced acceleration of a rise in stiffness in hypoperfused diabetic rat hearts

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)46456-1 ◽

1995 ◽

Vol 67 ◽

pp. 123

Author(s):

Makie Higuchi ◽

Kanako Miyagi ◽

Junko Nakasone ◽

Matao Sakanashi

Keyword(s):

Katp Channel ◽

K Channel ◽

Diabetic Rat ◽

Channel Opener ◽

K Channel Opener

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ChemInform Abstract: The Synthesis and Structure-Activity Relationships of 1,3-Diaryl 1,2,4-(4H)-Triazol-5-ones: A New Class of Calcium-Dependent, Large Conductance, Potassium (Maxi-K) Channel Opener Targeted for Urge Urinary Incontinence.

10.1002/chin.200230166 ◽

2010 ◽

Vol 33 (30) ◽

pp. no-no

Author(s):

Piyasena Hewawasam ◽

Matthew Erway ◽

George Thalody ◽

Harvey Weiner ◽

Christopher G. Boissard ◽

...

Keyword(s):

Urinary Incontinence ◽

Urge Urinary Incontinence ◽

K Channel ◽

Structure Activity Relationships ◽

Calcium Dependent ◽

New Class ◽

Structure Activity ◽

Channel Opener ◽

K Channel Opener

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Endothelium is involved in the vasorelaxation by an ATP-sensitive K+ channel opener, NIP-121

European Journal of Pharmacology ◽

10.1016/s0014-2999(98)00960-1 ◽

1999 ◽

Vol 366 (2-3) ◽

pp. R9-R10 ◽

Author(s):

Yoshio Tanaka ◽

Fumiko Yamaki ◽

Haruko Hirano ◽

Akiko Otsuka ◽

Hikaru Tanaka ◽

...

Keyword(s):

K Channel ◽

Channel Opener ◽

K Channel Opener

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A K+ channel opener in vascular smooth muscle: pharmacology and mechanism of action of cromakalim

Molecular Basis of Neurological Disorders and Their Treatment ◽

10.1007/978-94-011-3114-8_26 ◽

1991 ◽

pp. 272-288

Author(s):

U. Quast

Keyword(s):

Smooth Muscle ◽

Vascular Smooth Muscle ◽

Mechanism Of Action ◽

K Channel ◽

Channel Opener ◽

K Channel Opener

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Effects of Y-26763, an active metabolite of a new K channel opener Y-27152, on coronary and renal blood flow in anesthetized dogs.

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)39387-4 ◽

1991 ◽

Vol 55 ◽

pp. 333

Author(s):

Kiminori Kawahara ◽

Yoshiharu Hayashi ◽

Yukiya Hirata ◽

Jun Inui ◽

Kiyoteru Ikegami

Keyword(s):

Renal Blood Flow ◽

Active Metabolite ◽

K Channel ◽

Channel Opener ◽

Anesthetized Dogs ◽

K Channel Opener

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Cardioprotective effects of a long acting K+ channel opener Y-27152 under in vivo conditions

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)49686-8 ◽

1992 ◽

Vol 58 ◽

pp. 397

Author(s):

Kenji Shinagawa ◽

Atsushi Fukunari ◽

Hisato Miyai ◽

Tohru Nakajima

Keyword(s):

K Channel ◽

Channel Opener ◽

Cardioprotective Effects ◽

Long Acting ◽

K Channel Opener

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Protective effect of the K+ channel opener KRN4884 on peripheral arterial occlusive disease in rats

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)44992-5 ◽

1997 ◽

Vol 73 ◽

pp. 123

Author(s):

Yuji Okada ◽

Ikuko Ohshima ◽

Hideo Ohta ◽

Yasuhiro Jinno ◽

Tetsuya Yoshino ◽

...

Keyword(s):

Protective Effect ◽

Peripheral Arterial Occlusive Disease ◽

Arterial Occlusive Disease ◽

Occlusive Disease ◽

K Channel ◽

Channel Opener ◽

Peripheral Arterial ◽

K Channel Opener

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Inhaled Pinacidil, an ATP-Sensitive K+ Channel Opener, and Moguisteine Have Potent Antitussive Effects in Guinea Pigs

The Japanese Journal of Pharmacology ◽

10.1254/jjp.89.171 ◽

2002 ◽

Vol 89 (2) ◽

pp. 171-175 ◽

Author(s):

Kayo Morita ◽

Kenji Onodera ◽

Junzo Kamei

Keyword(s):

Guinea Pigs ◽

K Channel ◽

Channel Opener ◽

K Channel Opener

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