scholarly journals Determinants of Right Ventricular Muscle Mass in Idiopathic Dilated Cardiomyopathy: Impact of Left Ventricular Muscle Mass and Pulmonary Hypertension

2014 ◽  
Vol 11 (8) ◽  
pp. 834-840 ◽  
Author(s):  
Julia Vormbrock ◽  
Jeanette Liebeton ◽  
Sophia Wirdeier ◽  
Axel Meissner ◽  
Thomas Butz ◽  
...  
1991 ◽  
Vol 14 (2) ◽  
pp. 134-140 ◽  
Author(s):  
Jürgen Hüting ◽  
Veselin Mitrovic ◽  
Jochen Thormann ◽  
Hassan Bahavar ◽  
Martin Schlepper

2021 ◽  
Author(s):  
Stanislav Keranov ◽  
Oliver Dörr ◽  
Leili Jafari ◽  
Christoph Liebetrau ◽  
Till Keller ◽  
...  

Aim: This study assessed the utility of osteopontin (OPN) and galectin-3 (Gal-3) as biomarkers of maladaptive right ventricular remodeling in pulmonary hypertension (PH). Materials & methods: We examined plasma levels of OPN and Gal-3 in patients with PH (n = 62), dilated cardiomyopathy (n = 34), left ventricular hypertrophy (LVH; n = 47), and controls without right ventricle (RV) or LV abnormalities (n = 38). Results: OPN and Gal-3 levels were higher in PH, dilated cardiomyopathy and LVH than in the controls. OPN concentrations in PH patients with maladaptive RV were significantly higher than in those with adaptive RV. Gal-3 did not differentiate between adaptive and maladaptive RV remodeling in PH. OPN and Gal-3 levels did not correlate with parameters of LV remodeling. Conclusion: OPN is a potential biomarker of RV maladaptation.


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