scholarly journals Chemical modification of erythromycins. V. Synthesis and antibacterial activity of 4"-O-methyl derivatives of erythromycin A 11,12-cyclic carbonate.

1990 ◽  
Vol 43 (5) ◽  
pp. 566-569 ◽  
Author(s):  
SHIGEO MORIMOTO ◽  
YOKO MISAWA ◽  
HIDEAKI KONDOH ◽  
YOSHIAKI WATANABE ◽  
SADAFUMI OMURA
Keyword(s):  
Antibacterial Activity ◽  
Chemical Modification ◽  
Cyclic Carbonate ◽  
Methyl Derivatives ◽  
Erythromycin A ◽  
Derivatives Of

scholarly journals Chemical modification of erythromycins. II. Synthesis and antibacterial activity of O-alkyl derivatives of erythromycin A.

1990 ◽  
Vol 43 (3) ◽  
pp. 286-294 ◽  
Author(s):  
SHIGEO MORIMOTO ◽  
YOKO MISAWA ◽  
TAKASHI ADACHI ◽  
TAKATOSHI NAGATE ◽  
YOSHIAKI WATANABE ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Chemical Modification ◽  
Alkyl Derivatives ◽  
Erythromycin A ◽  
Derivatives Of

Synthesis and antibacterial activity of O-methyl derivatives of azalide antibiotics: II. 6-OMe derivatives VIA clarithromycin

1998 ◽  
Vol 8 (11) ◽  
pp. 1321-1326 ◽  
Author(s):  
Sherman T. Waddell ◽  
Gina M. Santorelli ◽  
Timothy A. Blizzard ◽  
Amy Graham ◽  
James Occi
Keyword(s):  
Antibacterial Activity ◽  
Methyl Derivatives ◽  
Derivatives Of

scholarly journals The use of deoxyfluoro-d-glucopyranoses and related compounds in a study of yeast hexokinase specificity

1972 ◽  
Vol 128 (2) ◽  
pp. 199-204 ◽  
Author(s):  
E. M. Bessell ◽  
A. B. Foster ◽  
J. H. Westwood
Keyword(s):  
Chemical Modification ◽  
Substrate Binding ◽  
Hexokinase 2 ◽  
Substantial Loss ◽  
Methyl Derivatives ◽  
Derivatives Of ◽  
Related Compounds ◽  
Yeast Hexokinase

1. 2-Deoxy-2-fluoro-d-glucose, 2-deoxy-2-fluoro-d-mannose and 2-deoxy-2,2-difluoro-d-arabino-hexose are good substrates for yeast hexokinase. 2. 3-Deoxy-3-fluoro-d-glucose and 4-deoxy-4-fluoro-d-glucose are poor substrates and have very similar Km values (8×10−2m). 3. Neither α- nor β-d-glucopyranosyl fluoride is a substrate or inhibitor. 4. Studies with 2-chloro-2-deoxy- and 2-O-methyl derivatives of d-glucose and d-mannose have revealed that little chemical modification is possible at position 2 without substantial loss in substrate binding. 5. The variation in the value of Km for the d-hexose derivatives was associated with a corresponding change in the value of Km for MgATP2− showing that the binding of MgATP2− is modified by the binding of the sugar.

ChemInform Abstract: Synthesis and Antibacterial Activity of New 4′′-O-Carbamates of 11,12-Cyclic Carbonate Erythromycin A 6,9-Imino Ether.

ChemInform ◽  
2011 ◽  
Vol 42 (31) ◽  
pp. no-no
Author(s):  
Ling Zhang ◽  
Bo Jiao ◽  
Xiangrui Yang ◽  
Lin Liu ◽  
Shutao Ma
Keyword(s):  
Antibacterial Activity ◽  
Cyclic Carbonate ◽  
Erythromycin A

scholarly journals Erratum: Synthesis and antibacterial activity of new 4′′-O-carbamates of 11,12-cyclic carbonate erythromycin A 6,9-imino ether

2012 ◽  
Vol 65 (2) ◽  
pp. 115-115
Author(s):  
Ling Zhang ◽  
Bo Jiao ◽  
Xiangrui Yang ◽  
Lin Liu ◽  
Shutao Ma
Keyword(s):  
Antibacterial Activity ◽  
Cyclic Carbonate ◽  
Erythromycin A

scholarly journals Synthesis and antibacterial activity of new 4″-O-carbamates of 11,12-cyclic carbonate erythromycin A 6,9-imino ether

2011 ◽  
Vol 64 (3) ◽  
pp. 243-247 ◽  
Author(s):  
Ling Zhang ◽  
Bo Jiao ◽  
Xiangrui Yang ◽  
Lin Liu ◽  
Shutao Ma
Keyword(s):  
Antibacterial Activity ◽  
Cyclic Carbonate ◽  
Erythromycin A

ChemInform Abstract: Synthesis and Antibacterial Activity of O-Methyl Derivatives of Azalide Antibiotics. Part 2. 6-OMe Derivatives via Clarithromycin.

ChemInform ◽  
2010 ◽  
Vol 29 (41) ◽  
pp. no-no
Author(s):  
S. T. WADDELL ◽  
G. M. SANTORELLI ◽  
T. A. BLIZZARD ◽  
A. GRAHAM ◽  
J. OCCI
Keyword(s):  
Antibacterial Activity ◽  
Methyl Derivatives ◽  
Derivatives Of
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