scholarly journals A Suspect Case of MAGIC Syndrome Showing Upper and Lower Respiratory Inflamemation Effectively Treated with Colchicine

2020 ◽  
Vol 59 (4) ◽  
pp. 406-414
Author(s):  
Masashi Yamamoto ◽  
Kayoko Kawashima ◽  
Mika Okuno ◽  
Hidenori Inohara
Keyword(s):  
Suspect Case ◽  
Magic Syndrome

scholarly journals Period prevalence and identification challenges of viral haemorrhagic fever suspect cases in a tertiary referral hospital in Guinea: a cross-sectional, retrospective study of triage and emergency room patient profiles

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Manuel Raab ◽  
Lisa M. Pfadenhauer ◽  
Vinh-Kim Nguyen ◽  
Dansira Doumbouya ◽  
Michael Hoelscher ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Emergency Room ◽  
Retrospective Chart Review ◽  
Laboratory Diagnostics ◽  
Haemorrhagic Fever ◽  
Case Definitions ◽  
Tertiary Referral Hospital ◽  
Cross Sectional ◽  
Viral Haemorrhagic Fever ◽  
Suspect Case

Abstract Background A functioning Viral Haemorrhagic Fever (VHF) surveillance system in countries at risk for outbreaks can reduce early transmission in case of an outbreak. Surveillance performance depends on the application of suspect case definitions in daily clinical practice. Recommended suspect case criteria during outbreaks are designed for high sensitivity and include general symptoms, pyrexia, haemorrhage, epidemiological link and unexplained death in patients. Non-outbreak criteria are narrower, relying on the persistence of fever and the presence of haemorrhagic signs. Methods This study ascertains VHF suspect case prevalence based on outbreak and non-outbreak criteria in a Guinean regional hospital for a period of three months. The study further describes clinical trajectories of patients who meet non-outbreak VHF suspect case criteria in order to discuss challenges in their identification. We used cross-sectional data collection at triage and emergency room to record demographic and clinical data of all admitted patients during the study period. For the follow-up study with description of diagnostic trajectories of VHF suspect cases, we used retrospective chart review. Results The most common symptoms of all patients upon admission were fever, tiredness/weakness and abdominal pain. 686 patients met EVD outbreak criteria, ten adult patients and two paediatric patients met study-specific non-outbreak VHF suspect case criteria. None of the suspect cases was treated as VHF suspect case and none tested positive for malaria upon admission. Their most frequent discharge diagnosis was unspecific gastrointestinal infection. The most common diagnostic measures were haemoglobin level and glycaemia for both adults and for children; of the requested examinations for hospitalized suspect cases, 36% were not executed or obtained. Half of those patients self-discharged against medical advice. Conclusions Our study shows that the number of VHF suspect cases may vary greatly depending on which suspect case criteria are applied. Identification of VHF suspect cases seems challenging in clinical practice. We suggest that this may be due to the low use of laboratory diagnostics to support certain diagnoses and the non-application of VHF suspect case definitions in clinical practice. Future VHF suspect case management should aim to tackle such challenges in comparable hospital settings.

Manifestations neurologiques révélant un MAGIC syndrome

2019 ◽  
Vol 175 ◽  
pp. S139
Author(s):  
Chahrazad Boukadir ◽  
Hakim Si Ahmed ◽  
Nadjia Ababou ◽  
Ouiza Belkhamsa ◽  
Smail Daoudi
Keyword(s):  
Magic Syndrome

Transverse Aortic Arch Replacement Associated with MAGIC Syndrome: Case Report and Literature Review

2006 ◽  
Vol 20 (3) ◽  
pp. 395-398 ◽  
Author(s):  
Manuel Caceres ◽  
Anthony L. Estrera ◽  
L. Maximilian Buja ◽  
Hazim J. Safi
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Aortic Arch ◽  
Aortic Arch Replacement ◽  
Magic Syndrome

scholarly journals Aortic aneurysm in MAGIC syndrome successfully managed with combined anti-TNF-  and stent grafting

Rheumatology ◽  
2009 ◽  
Vol 48 (9) ◽  
pp. 1169-1170 ◽  
Author(s):  
A. Mekinian ◽  
M. Lambert ◽  
J.-P. Beregi ◽  
S. Morell-Dubois ◽  
D. Launay ◽  
...  
Keyword(s):  
Aortic Aneurysm ◽  
Stent Grafting ◽  
Magic Syndrome

Editorial: Advising the Suspect Case

1947 ◽  
Vol 62 (10) ◽  
pp. 325
Author(s):  
Herman E. Hilleboe
Keyword(s):  
Suspect Case

scholarly journals Knowledge, attitudes and practices towards viral haemorrhagic fevers amongst healthcare workers in urban and rural public healthcare facilities in the N’zérékoré Prefecture, Guinea: a cross-sectional study

2020 ◽  
Author(s):  
Manuel Raab ◽  
Lisa M. Pfadenhauer ◽  
Tamba Jacques Millimouno ◽  
Michael Hoelscher ◽  
Guenter Froeschl
Keyword(s):  
Healthcare Workers ◽  
Good Knowledge ◽  
Infection Prevention And Control ◽  
Public Healthcare ◽  
Case Detection ◽  
Rural Healthcare ◽  
Healthcare Facilities ◽  
Attitudes And Practices ◽  
Knowledge Attitudes And Practices ◽  
Suspect Case

Abstract Introduction: The 2013-2016 Ebola epidemic in West Africa began in Guinea’s Forest region, a region now considered to be at high risk for future epidemics of viral haemorrhagic fevers (VHF). Good knowledge, attitudes and practices towards VHF amongst healthcare workers in such regions are a central pillar of infection prevention and control (IPC). To inform future training in IPC, this study assesses the knowledge, attitudes and practices (KAP) towards VHF amongst healthcare workers in public healthcare facilities in the most populated prefecture in Forest Guinea, and compares results from urban and rural areas. Methods: In June and July 2019, we interviewed 102 healthcare workers in the main urban and rural public healthcare facilities in the N’zérékoré prefecture in Forest Guinea. We used an interviewer-administered questionnaire adapted from validated KAP surveys. Results: The great majority of respondents demonstrated good knowledge and favourable attitudes towards VHF. However, respondents reported some gaps in preventive practices such as VHF suspect case detection. They also reported a shortage of protective medical equipment used in everyday clinical work in both urban and rural healthcare facilities and a lack of training in IPC, especially in rural healthcare facilities. However, whether or not healthcare workers had been trained in IPC did not seem to influence their level of KAP towards VHF. Conclusions: Three years after the end of the Ebola epidemic, our findings suggest that public healthcare facilities in the N’zérékoré prefecture in Forest Guinea still lack essential protective equipment and some practical training in VHF suspect case detection. To minimize the risk of future VHF epidemics and improve management of outbreaks of infectious diseases in the region, current efforts to strengthen the public healthcare system in Guinea should encompass questions of supply and IPC training.

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