scholarly journals Peer Review #4 of "Prognostic value of mean platelet volume/platelet count ratio in patients with resectable esophageal squamous cell carcinoma: a retrospective study (v0.1)"

2019 ◽  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Platelet Count ◽  
Retrospective Study ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Peer Review ◽  
Mean Platelet Volume ◽  
Prognostic Value ◽  
Platelet Volume ◽  
Resectable Esophageal

scholarly journals Prognostic value of mean platelet volume/platelet count ratio in patients with resectable esophageal squamous cell carcinoma: a retrospective study

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e7246
Author(s):  
Ji-Feng Feng ◽  
Chen Sheng ◽  
Qiang Zhao ◽  
Pengcheng Chen
Keyword(s):  
Squamous Cell Carcinoma ◽  
Platelet Count ◽  
Retrospective Study ◽  
Esophageal Squamous Cell Carcinoma ◽  
Roc Curve ◽  
Mean Platelet Volume ◽  
Multivariate Analyses ◽  
Independent Predictor ◽  
Roc Curves ◽  
Platelet Volume

Background Mean platelet volume (MPV) to platelet count (PC) ratio (MPV/PC) is a useful indicator in several cancers. However, the role for MPV/PC ratio in esophageal squamous cell carcinoma (ESCC) is still controversial. Methods A retrospective study was conducted including 277 resectable ESCC patients. The optimal cut-off values were calculated by the X-tile program. The receiver operator characteristic (ROC) curves were also created to show the candidate cut-off points. The comparisons between the X-tile plot and ROC curve were performed. The Kaplan-Meier method was utilized to analyze the cancer-specific survival (CSS). Prognostic factors for CSS were calculated with Cox regression univariate and multivariate analyses. Results According to the X-tile program, the cut-off values for MPV, PC and MPV/PC ratio were 8.5 (fl), 200 (giga/l) and 0.04, respectively. However, the cut-off values for MPV, PC and MPV/PC ratio by the ROC curves were 8.25 (fl), 243.5 (giga/l) and 0.0410, respectively. The cut-off values were similar between the X-tile and ROC curve. A low MPV/PC ratio level (≤0.04) was associated with poor CSS (22.4% vs. 43.1%, P < 0.001). In multivariate analyses, we found that MPV/PC ratio was an independent predictor for CSS (P < 0.001). When we set the cut-off point using ROC curve, the MPV/PC ratio was still an independent predictor for CSS (P < 0.001). Conclusion The MPV/PC ratio is a useful predictive indicator in patients with ESCC.

Expression and Prognostic Value of MG7-Ag in Patients With Surgically Resectable Esophageal Squamous Cell Carcinoma

2007 ◽  
Vol 14 (9) ◽  
pp. 2621-2627 ◽  
Author(s):  
Yunping Zhao ◽  
Yaoguang Jiang ◽  
Ruwen Wang ◽  
Xiushan Zheng ◽  
Xin Wang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Prognostic Value ◽  
Resectable Esophageal
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