Highly Active Antiretroviral Therapy Decreases Mortality and Morbidity in Patients with Advanced HIV Disease

2001 ◽  
Vol 135 (1) ◽  
pp. 17 ◽  
Author(s):  
Edward L. Murphy ◽  
Ann C. Collier ◽  
Leslie A. Kalish ◽  
Susan F. Assmann ◽  
Michael F. Para ◽  
...  
AIDS ◽  
2001 ◽  
Vol 15 (18) ◽  
pp. 2453-2455 ◽  
Author(s):  
Fiona M. Burns ◽  
Ade O. Fakoya ◽  
Andrew J. Copas ◽  
Patrick D. French

2007 ◽  
Vol 36 (3) ◽  
pp. 136-141 ◽  
Author(s):  
K. M. R. Umadevi ◽  
K. Ranganathan ◽  
S. Pavithra ◽  
R. Hemalatha ◽  
T. R. Saraswathi ◽  
...  

2000 ◽  
Vol 77 (2) ◽  
pp. 150-165 ◽  
Author(s):  
Barbara Greenberg ◽  
Ruth Mccorkle ◽  
David Vlahov ◽  
Peter A. Selwyn

2006 ◽  
Vol 17 (3) ◽  
pp. 205-207 ◽  
Author(s):  
Simon Rackstraw ◽  
Jeanette Meadway ◽  
James Bingham ◽  
Safa Al-Sarraj ◽  
Ian Everall

We report an individual who had HIV-associated dementia, but a good clinical response to antiretroviral therapy, with a rising CD4 count and undetectable viral load. A severe leukoencephalopathy was noted at postmortem; however, no HIV immunopositive cells were found in the brain, suggesting that this new severe leukoencephalopathy is associated with immune reconstitution.


2006 ◽  
Vol 19 (1) ◽  
pp. 17-30 ◽  
Author(s):  
Melody L. Duffalo

Fungal pathogens can lead to many of the complications seen in advanced HIV disease and are commonly identified in HIV-infected populations with decreased immune function. Common fungal organisms affecting individuals with AIDS include Cryptococcus neoformans, various Candida species, and Histoplasma capsulatum. While infection with these organisms can be fatal, appropriate identification and management of the condition can result in reduced mortality and the opportunity for effectivemanagement of HIV disease with highly active antiretroviral therapy. This article describes the clinical presentation and treatment of 3 fungal infections common in the immunocompromised individual with AIDS. Current antifungal therapy for themanagement of these infections is discussed. In addition, the role of newer antifungal agents in the setting of these conditions is reviewed.


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