Herpes Simplex Virus–Associated Sepsis in a Previously Infected Immunocompetent Adult

2003 ◽  
Vol 139 (2) ◽  
pp. 153 ◽  
Author(s):  
George Zahariadis
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Immunocompetent Adult ◽  
Simplex Virus

scholarly journals Trillions and Trillions: Herpes Simplex Virus–1 Hepatitis in an Immunocompetent Adult

2019 ◽  
Vol 6 (11) ◽  
Author(s):  
Kevin Ikuta ◽  
Pavitra Roychoudhury ◽  
Hong Xie ◽  
Christopher L Mcclurkan ◽  
Magdalena Walkiewicz ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Cell Response ◽  
T Cell Response ◽  
Immunocompetent Adult ◽  
Herpes Simplex Virus 1 ◽  
Simplex Virus ◽  
Hsv 1

Abstract We describe a case of acute liver failure and myopericarditis due to herpes simplex virus–1 (HSV-1) in an immunocompetent adult. We estimate that, at the height of viremia, the patient contained a quantity of HSV-1 virions approaching that of human cells. The patient recovered with acyclovir that was dose-adjusted for neurotoxicity and developed a vigorous anti-HSV-1 T-cell response.

scholarly journals Herpes simplex virus associated sepsis in an immunocompetent adult

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Shan Li ◽  
Wei Jiang ◽  
Jin-Min Peng ◽  
Bin Du ◽  
Li Weng
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Immunocompetent Adult ◽  
Simplex Virus

scholarly journals Herpes Simplex Virus Type 2 Encephalitis with Herpes Simplex Virus Type 1 MRI Findings in an Immunocompetent Adult

2021 ◽  
Vol 4 (6) ◽  
pp. 125-127
Author(s):  
Lintu Ramachandran ◽  
Vibhav K Bansal ◽  
Muhammad Janjua ◽  
Taha Mohamed Djirdeh ◽  
Janine Borja
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Mri Findings ◽  
Immunocompetent Adult ◽  
Simplex Virus

Fulminant hepatitis from herpes simplex virus type 2 in an immunocompetent adult

2007 ◽  
Vol 9 (4) ◽  
pp. 323-326 ◽  
Author(s):  
L. Abbo ◽  
M.L. Alcaide ◽  
J.R. Pano ◽  
P.G. Robinson ◽  
R.E. Campo
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Fulminant Hepatitis ◽  
Immunocompetent Adult ◽  
Simplex Virus

Severe Oropharyngitis due to Herpes Simplex Virus Type 2 Infection in an Immunocompetent Adult

2015 ◽  
Vol 110 (8) ◽  
pp. 1140 ◽  
Author(s):  
Koichiro Abe ◽  
Hitoshi Aoyagi ◽  
Norihisa Okada ◽  
Koji Saito ◽  
Yasushi Kuyama
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Immunocompetent Adult ◽  
Simplex Virus

Assembly of VP26 in herpes simplex virus-1 capsid implicated by 3-D structure of recombinant capsid

1995 ◽  
Vol 53 ◽  
pp. 840-841
Author(s):  
Z. Hong Zhou ◽  
Jing He ◽  
Joanita Jakana ◽  
J. D. Tatman ◽  
Frazer J. Rixon ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
3D Structure ◽  
Structure Study ◽  
Herpes Simplex Virus 1 ◽  
Shell Proteins ◽  
Life Threatening ◽  
Infected Cells ◽  
Simplex Virus ◽  
Hsv 1

Herpes simplex virus-1 (HSV-1) is a ubiquitous virus which is implicated in diseases ranging from self-curing cold sores to life-threatening infections. The 2500 Å diameter herpes virion is composed of a glycoprotein spike containing, lipid envelope, enclosing a protein layer (the tegument) in which is embedded the capsid (which contains the dsDNA genome). The B-, and A- and C-capsids, representing different morphogenetic stages in HSV-1 infected cells, are composed of 7, and 5 structural proteins respectively. The three capsid types are organized in similar T=16 icosahedral shells with 12 pentons, 150 hexons, and 320 connecting triplexes. Our previous 3D structure study at 26 Å revealed domain features of all these structural components and suggested probable locations for the outer shell proteins, VP5, VP26, VP19c and VP23. VP5 makes up most of both pentons and hexons. VP26 appeared to bind to the VP5 subunit in hexon but not to that in penton.

Application of EM to differentiate herpes virus from pox virus in genital specimens

1994 ◽  
Vol 52 ◽  
pp. 262-263
Author(s):  
K. Rekrut ◽  
K. Schleuter
Keyword(s):  
Tissue Culture ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Fresh Tissue ◽  
Culture Cells ◽  
Viral Transport ◽  
Carbon Coated ◽  
Immuno Assay ◽  
Simplex Virus ◽  
Enzyme Immuno Assay

Confirmation of herpes simplex virus (HSV) from genital lesions of obstetrical (OB) patients may affect both the management of the delivery and of the neonate.(l,2) During 1992 and 1993, 4,450 genital specimens from OB patients were submitted in viral transport media for herpes culture. The specimens were inoculated into MRC-5, Vero, and A-549 tissue culture tubes, incubated, and examined daily for 7 days for cytopathic effect (CPE). The original specimens were frozen at −70° C until final reports were issued. Culture tubes with CPE were tested by the Dupont Herpchek enzyme immuno assay (EIA) to confirm the presence of herpes simplex virus (HSV). (3,4) 170 OB patient specimens were positive by culture and confirmed by EIA.There were also 63 cultures exhibiting CPE ressembling HSV which were negative by EIA testing, which failed to pass in fresh tissue culture cells or progress to more enhanced CPE in culture. These original specimens were screened by electron microscopy after direct ultracentrifugation employing the Beckman airfuge with the EM 90 rotor on to formvar carbon-coated 300 mesh copper grids and negatively stained with 2% PTA.

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