scholarly journals Long-term immune responses and comparative effectiveness of one or two doses of 7-valent pneumococcal conjugate vaccine (PCV7) in HIV-positive adults in the era of combination antiretroviral therapy

2016 ◽  
Vol 19 (1) ◽  
pp. 20631 ◽  
Author(s):  
Aristine Cheng ◽  
Sui-Yuan Chang ◽  
Mao-Song Tsai ◽  
Yi-Ching Su ◽  
Wen-Chun Liu ◽  
...  
2016 ◽  
pp. jiw605 ◽  
Author(s):  
Aristine Cheng ◽  
Sui-Yuan Chang ◽  
Hsin-Yun Sun ◽  
Mao-Song Tsai ◽  
Wen-Chun Liu ◽  
...  

2000 ◽  
Vol 74 (15) ◽  
pp. 6984-6991 ◽  
Author(s):  
Katherine Luzuriaga ◽  
Margaret McManus ◽  
Michelle Catalina ◽  
Shane Mayack ◽  
Mark Sharkey ◽  
...  

ABSTRACT Studies of potent antiretroviral combination regimens were undertaken in young infants to evaluate the potential for long-term suppression of viral replication and to evaluate the immune consequences of such therapies. Early combination antiretroviral therapy led to a loss of plasma viremia, cultivable virus, and labile extrachromosomal replication intermediates. Despite preservation of immune function, persistent human immunodeficiency type 1 (HIV-1)-specific immune responses were not detected in most infants. The absence of detectable, persisting immune responses in most HIV-1-infected infants treated early contrasts with what is typically seen in adults who are treated early. These results are consistent with the notion that early combination antiretroviral therapy of HIV-1-infected infants allows the long-term suppression of viral replication.


AIDS ◽  
2017 ◽  
Vol 31 ◽  
pp. S31-S40 ◽  
Author(s):  
Nanina Anderegg ◽  
Leigh F. Johnson ◽  
Elizabeth Zaniewski ◽  
Keri N. Althoff ◽  
Eric Balestre ◽  
...  

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