scholarly journals Correlation Between Central Corneal Thickness and Radial Peripapillary Capillary Density, in Patients With Ocular Hypertension

Cureus ◽  
2021 ◽  
Author(s):  
Elpida Kollia ◽  
Eleni Patsea ◽  
Ilias Georgalas ◽  
Dimitrios Brouzas ◽  
Dimitrios Papaconstantinou
2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Shih-Chun Chao ◽  
Shang-Jung Yang ◽  
Hung-Chi Chen ◽  
Chi-Chin Sun ◽  
Chin-Hsin Liu ◽  
...  

Purpose. To evaluate early macular circulation in open-angle glaucoma (OAG), normal-tension glaucoma (NTG), ocular hypertension (OHT), and healthy subjects via optical coherence tomography angiography (OCTA). Methods. A retrospective cross-sectional study was conducted. Medical records were reviewed, and the patients who received OCTA examinations were divided into the OAG, NTG, OHT, and normal groups. The ophthalmic data including best-corrected visual acuity, spherical equivalent, intraocular pressure, central corneal thickness, central foveal thickness, visual field deviation, retinal nerve fiber layers thickness, and ganglion cell complex thickness were obtained from medical documents. For the macular area, the superficial vessel density (VD), deep VD, foveal avascular zone (FAZ), flow area of the outer retina, and flow area of the choriocapillaris were measured via OCTA and analyzed using the default vascular density analysis program in the same OCTA device. Results. A total of 70 eyes from 70 patients were analyzed in the current study. Significant differences in the intraocular pressure, central corneal thickness, visual field deviation, retinal fiber layer thickness, and ganglion cell complex thickness were observed in the patients in the glaucoma group at their last visits. The OAG and NTG groups evinced a lower superficial VD than did the control group, while the NTG group had a lower deep VD than the control group. The NTG group also had a larger FAZ than did the OHT group. The flow area of the outer retina in the OAG group was low relative to those of the OHT and control groups. No difference in choriocapillaris perfusion was observed among the groups. Conclusion. The OAG and NTG patients demonstrated impaired vasculature before significant disease development could be observed. Furthermore, the differences in macular circulation may be associated with differences in the courses of disease between the glaucoma and OHT patients.


2001 ◽  
Vol 239 (6) ◽  
pp. 463-463
Author(s):  
Consuelo Gutierrez ◽  
Jose R. V. Casaponsa ◽  
Francisco Munoz ◽  
Gema Rebolleda

2020 ◽  
Vol 10 (5) ◽  
pp. 132-135
Author(s):  
Hina Manzoor ◽  
Asma Batool ◽  
Saba Akram ◽  
Iqra Khalil ◽  
Ammara Affi

Purpose: Purpose of this study is to determine the relationship between Post-op central corneal thickness and steroid-induced ocular hypertension following myopic photorefractive keratectomy. Methods: This longitudinal analytical study was carried on 50 patients, both gender and age ranging from 20-40 years who had undergone myopic PRK refractive surgery. The data collected from The Department of Ophthalmology in Madina Teaching Hospital Faisalabad in the duration of 11 months from July 2019 to May 2020. IOP measured by Goldmann applanation tonometer. Recorded IOP greater than 21mmHg was considered as Ocular hypertension (OHT). The post-Op follow-up was conducted 1 day, 1 week, 2-3 weeks, and 4-6 weeks. The CCT and IOP was evaluated carefully. Data was noted on Performa. Data was analyzed by using Descriptive and Repeated Measures ANOVA by using the latest version 21 of SPSS. Results: Out of 50 patients’ 46% were males and 54% were females. The mean score of CCT pre & post operatively for right eye and left eye was 529.28±34.74 & 462.56±40.20 and 529.18±37.2, 462.44±42.60 respectively. Statistically significant effect was seen on post-op central corneal thickness and steroid induced ocular hypertension, according to the results of repeated measure ANOVA. Thinner corneas were more susceptible to steroids induced OHT. In various post-op central corneal thickness, it was observed that patients with thinner corneal thickness ranges 413±4.24 to 449.33±48.29 in right eye and 455.8±56.42 to 456.83±50.52 are more affected by topical steroids used. Males were more affected than females due to decreased central corneal thickness. Elderly patients were more susceptible to steroid-induced ocular hypertension post-operatively. Conclusion: Post-op steroid induced ocular hypertension is affecting by central corneal thickness. Male and elderly individual are more susceptible to steroid-induced ocular hypertension following myopic PRK. Post-Op use of topical steroids cause ocular hypertension in thinner corneas


Ophthalmology ◽  
2020 ◽  
Vol 127 (4) ◽  
pp. S72-S81
Author(s):  
James D. Brandt ◽  
Julia A. Beiser ◽  
Michael A. Kass ◽  
Mae O. Gordon

Author(s):  
Alan D. Penman ◽  
Kimberly W. Crowder ◽  
William M. Watkins

The Ocular Hypertension Treatment Study (OHTS) was a randomized, open, placebo-controlled, clinical trial to determine whether reducing intraocular pressure (IOP) in eyes with ocular hypertension (OHTN) reduced the risk of developing primary open-angle glaucoma (POAG). The study found that topical ocular hypotensive medication was effective in delaying or preventing the development of glaucomatous optic neuropathy in eyes with OHTN. However, the authors recommended stratifying risk in patients with OHTN using variables such as baseline age, vertical and horizontal cup-to-disc ratio, visual field pattern standard deviation, IOP, and, especially, central corneal thickness.


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