scholarly journals The study of cytoskeletal regulators on cell motility using Dictyostelium discoideum as a model organism with a view to human application in Marfan's syndrome and valvular diseases

2016 ◽  
Vol 16 (Suppl 3) ◽  
pp. s29-s29
Author(s):  
Gaurav Kataria
Keyword(s):  
Cell Motility ◽  
Dictyostelium Discoideum ◽  
Model Organism ◽  
Marfan’S Syndrome ◽  
Marfan's Syndrome ◽  
Valvular Diseases

scholarly journals The Dictyostelium discoideum model system

2019 ◽  
Vol 63 (8-9-10) ◽  
pp. 317-320 ◽  
Author(s):  
Ricardo Escalante ◽  
Elena Cardenal-Muñoz
Keyword(s):  
Cell Motility ◽  
Dictyostelium Discoideum ◽  
Cell Biology ◽  
Model Organism ◽  
Opportunity To Learn ◽  
Model System ◽  
Special Issue ◽  
Complete Understanding ◽  
Single Model ◽  
Present Collection

When we set out to organize this Special Issue, we faced the difficult task of gathering together a large variety of topics with the unique commonality of having been studied in a single model organism, Dictyostelium discoideum. This apparent setback turned into a wonderful opportunity to learn about an organism as a whole, which provides a more complete understanding of life processes, their natural meaning and their changes during evolution. From studies dedicated almost exclusively to cell motility, differentiation and patterning, the versatility of D. discoideum has allowed in recent years the expansion of our knowledge to other areas, including cell biology and many others related to human diseases. The present collection of papers can be considered as a journey throughout the mechanisms of life, where D. discoideum acts as a very special tourist guide.

Concurrence of Marfan's syndrome and von Recklinghausen's disease with the development of malignant schwannoma.

1987 ◽  
Vol 49 (3) ◽  
pp. 460-464
Author(s):  
Kazumoto KATAGIRI ◽  
Tomohito HONDA ◽  
Satoshi ITAMI ◽  
Etsuji MATSUNAGA ◽  
Hiroshi SHINKAI ◽  
...  
Keyword(s):  
Malignant Schwannoma ◽  
Von Recklinghausen’S Disease ◽  
Marfan’S Syndrome ◽  
Von Recklinghausen's Disease ◽  
Marfan's Syndrome ◽  
Recklinghausen's Disease ◽  
Recklinghausen’S Disease

scholarly journals The distribution of myosin II in Dictyostelium discoideum slug cells.

1991 ◽  
Vol 115 (5) ◽  
pp. 1267-1274 ◽  
Author(s):  
S Eliott ◽  
P H Vardy ◽  
K L Williams
Keyword(s):  
Cell Motility ◽  
Dictyostelium Discoideum ◽  
Immunofluorescence Microscopy ◽  
Molecular Genetic ◽  
Myosin Ii ◽  
Three Dimensional ◽  
Homogeneous Distribution ◽  
Multicellular Development ◽  
Insight Into

While the role of myosin II in muscle contraction has been well characterized, less is known about the role of myosin II in non-muscle cells. Recent molecular genetic experiments on Dictyostelium discoideum show that myosin II is necessary for cytokinesis and multicellular development. Here we use immunofluorescence microscopy with monoclonal and polyclonal antimyosin antibodies to visualize myosin II in cells of the multicellular D. discoideum slug. A subpopulation of peripheral and anterior cells label brightly with antimyosin II antibodies, and many of these cells display a polarized intracellular distribution of myosin II. Other cells in the slug label less brightly and their cytoplasm displays a more homogeneous distribution of myosin II. These results provide insight into cell motility within a three-dimensional tissue and they are discussed in relation to the possible roles of myosin II in multicellular development.

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