Transvaginal oocyte retrieval (TVOR) for in vitro fertilization (IVF) is a standard procedure with very few complications. Although a relatively safe procedure immediate complications like bleeding from the vaginal vault, hemoperitoneum and trauma to the adjoining structures like the bladder, ureter etc and delayed complications like pelvic abscess and fistulas have been reported in literature. We report a case of 29 year old women with past history of pelvic inflammatory disease (PID) who underwent TVOR for IVF and later on presented with right side pyosalpingx, a delayed complication of TVOR. The patient had to undergo salpingectomy. Late manifestation of pyosalpingx supports the notion that the presence of PID is a high risk for infective complications following any pelvic procedure as it provides a culture medium for bacteria to grow slowly after transvaginal inoculation.