Crude Aloe vera Gel Reduces Small Intestinal Transit and Increases Body Weight in Normal Albino Wistar Rats

2013 ◽  
Vol 2 (2) ◽  
pp. 741-753
Author(s):  
Nna Udo
Keyword(s):  
Body Weight ◽  
Wistar Rats ◽  
Aloe Vera ◽  
Intestinal Transit ◽  
Small Intestinal Transit ◽  
Aloe Vera Gel ◽  
Small Intestinal

Effect of a Polyphenol-Rich Extract from Aloe vera Gel on Experimentally Induced Insulin Resistance in Mice

2007 ◽  
Vol 35 (06) ◽  
pp. 1037-1046 ◽  
Author(s):  
Yolanda Y. Pérez ◽  
Enrique Jiménez-Ferrer ◽  
Alejandro Zamilpa ◽  
Marcelino Hernández-Valencia ◽  
Francisco J. Alarcón-Aguilar ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Body Weight ◽  
Aloe Vera ◽  
Negative Control Group ◽  
Negative Control ◽  
Control Group ◽  
Glucose Levels ◽  
Insulin Tolerance ◽  
Aloe Vera Gel ◽  
Experimentally Induced

Insulin resistance, which precedes type 2 diabetes mellitus (T2DM), is a widespread pathology associated with the metabolic syndrome, myocardial ischemia, and hypertension. Finding an adequate treatment for this pathology is an important goal in medicine. The purpose of the present research was to investigate the effect of an extract from Aloe vera gel containing a high concentration of polyphenols on experimentally induced insulin resistance in mice. A polyphenol-rich Aloe vera extract (350 mg/kg) with known concentrations of aloin (181.7 mg/g) and aloe-emodin (3.6 mg/g) was administered orally for a period of 4 weeks to insulin resistant ICR mice. Pioglitazone (50 mg/kg) and bi-distilled water were used as positive and negative controls respectively. Body weight, food intake, and plasma concentrations of insulin and glucose were measured and insulin tolerance tests were performed. The insulin resistance value was calculated using the homeostasis model assessment for insulin resistance (HOMA-IR) formula. Results showed that the polyphenol-rich extract from Aloe vera was able to decrease significantly both body weight ( p < 0.008) and blood glucose levels ( p < 0.005) and to protect animals against unfavorable results on HOMA-IR, which was observed in the negative control group. The highest glucose levels during the insulin tolerance curve test were in the negative control group when compared to the Aloe vera extract and pioglitazone treated mice ( p < 0.05). In conclusion, Aloe vera gel could be effective for the control of insulin resistance.

scholarly journals Delayed small-intestinal transit in tropical malabsorption.

BMJ ◽  
1978 ◽  
Vol 2 (6132) ◽  
pp. 238-240 ◽  
Author(s):  
G C Cook
Keyword(s):  
Intestinal Transit ◽  
Small Intestinal Transit ◽  
Small Intestinal

Blockade of GRP receptors inhibits gastric emptying and gallbladder contraction but accelerates small intestinal transit in humans

2000 ◽  
Vol 94 (1-3) ◽  
pp. 9
Author(s):  
Pius Hildebrand ◽  
Lukas P. Degen ◽  
Annette Collet ◽  
Livio Rossi ◽  
Fuping Peng ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Intestinal Transit ◽  
Gallbladder Contraction ◽  
Small Intestinal Transit ◽  
Small Intestinal ◽  
Grp Receptors

Exercise and small intestinal transit

1987 ◽  
Vol 8 (2) ◽  
pp. 105-110 ◽  
Author(s):  
KATHERINE J. OLLERENSHAW ◽  
SARAH NORMAN ◽  
CLIVE G. WILSON ◽  
JOHN G. HARDY
Keyword(s):  
Intestinal Transit ◽  
Small Intestinal Transit ◽  
Small Intestinal
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