scholarly journals Successful Combination Therapy of Radical Liver Resection With 5-Fluorouracil/leucovorin, Oxaliplatin, Plus Bevacizumab for Ascending Colon Cancer With Pulmonary and 43 Liver Metastases: Report of a Case

2012 ◽  
Vol 97 (1) ◽  
pp. 6-13
Author(s):  
Takanori Ochiai ◽  
Taiki Masuda ◽  
Masayuki Yagi ◽  
Reo Kasai ◽  
Takaki Furuyama ◽  
...  
Keyword(s):  
Liver Resection ◽  
Liver Metastases ◽  
Liver Tumors ◽  
Lung Metastases ◽  
Right Hemicolectomy ◽  
Ascending Colon ◽  
Node Dissection ◽  
Caudal Lobe ◽  
Metastatic Lesions ◽  
Ascending Colon Cancer

Abstract At the time of diagnosis, 20% to 25% of patients with colorectal cancer already have liver metastases, the presence of which is a most important prognostic factor. A 64-year-old man was admitted to our hospital for investigation of anemia and multiple liver tumors. Examinations revealed ascending colon carcinoma with more than 40 liver metastases and 2 lung metastases. We performed right hemicolectomy with lymph node dissection, which was followed by 5-fluorouracil/leucovorin, oxaliplatin, plus bevacizumab (FOLFOX-BV). After 4 courses of chemotherapy, the lung metastases were in complete remission and the liver metastases had shrunk. We suggested the option of radical liver resection, but the patient declined initially as he had not suffered any severe side effects of FOLFOX-BV. After 23 courses of the chemotherapy, he agreed to undergo hepatectomy. We performed extended right lobectomy with partial left and caudal lobe resection. All of the macroscopic metastatic lesions were resected. Histopathologically, viable cancer cells were recognized in 7 of the 43 liver metastatic lesions. Postoperatively, FOLFOX-BV was restarted and continued for 10 months. At the time of writing, 15 months after the hepatectomy, the patient was well without evidence of recurrence of the cancer.

scholarly journals Pathological Complete Response after Systemic Chemotherapy for an Ascending Colon Cancer with Unresectable Multiple Liver Metastases

2014 ◽  
Vol 47 (4) ◽  
pp. 230-237
Author(s):  
Taisuke Baba ◽  
Ryuzo Yamaguchi ◽  
Miho Furuta ◽  
Akitoshi Sasamoto ◽  
Shinya Watanabe ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Liver Metastases ◽  
Systemic Chemotherapy ◽  
Pathological Complete Response ◽  
Complete Response ◽  
Ascending Colon ◽  
Ascending Colon Cancer ◽  
Multiple Liver Metastases

scholarly journals A case of ascending colon cancer accompanied with tumor thrombosis in the superior mesenteric vein treated with right hemicolectomy and greater saphenous vein grafting

2018 ◽  
Vol 51 ◽  
pp. 358-363 ◽  
Author(s):  
Shintaro Akabane ◽  
Shoichiro Mukai ◽  
Hiroyuki Egi ◽  
Tomohiro Adachi ◽  
Masatoshi Kochi ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Saphenous Vein ◽  
Superior Mesenteric Vein ◽  
Right Hemicolectomy ◽  
Ascending Colon ◽  
Mesenteric Vein ◽  
Tumor Thrombosis ◽  
Ascending Colon Cancer

Laparoscopic right hemicolectomy for metachronous ascending colon cancer with preservation of an ileal conduit constructed after previous radical cystectomy for bladder cancer

2015 ◽  
Vol 8 (2) ◽  
pp. 188-192 ◽  
Author(s):  
Kae Okoshi ◽  
Suguru Hasegawa ◽  
Teppei Murakami ◽  
Masahiro Yamada ◽  
Koya Hida ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Bladder Cancer ◽  
Radical Cystectomy ◽  
Ileal Conduit ◽  
Right Hemicolectomy ◽  
Ascending Colon ◽  
Ascending Colon Cancer ◽  
Laparoscopic Right Hemicolectomy

Life-threating intraoperative intestinal congestion by unforeseen SMV torsion during pancreaticoduodenectomy for local recurrence of ascending colon cancer in a patient with a prior right hemicolectomy: A case report

Pancreatology ◽  
2016 ◽  
Vol 16 (4) ◽  
pp. S129
Author(s):  
Koji Fujimoto ◽  
Yujiro Kokado ◽  
Hikotaro Katsura ◽  
Takashi Komatsubara ◽  
Hidekazu Nishigori ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Case Report ◽  
Local Recurrence ◽  
Right Hemicolectomy ◽  
Ascending Colon ◽  
Ascending Colon Cancer

Rapid Growth of a Retroperitoneal Rhabdomyosarcoma Following Right Hemicolectomy for Ascending Colon Cancer: Report of a Case

Surgery Today ◽  
2000 ◽  
Vol 30 (4) ◽  
pp. 372-375 ◽  
Author(s):  
Katsuyuki Kunieda ◽  
Shigetoyo Saji ◽  
Ikuhide Kuwabara ◽  
Atsushi Watanabe ◽  
Motohisa Katoh ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Rapid Growth ◽  
Right Hemicolectomy ◽  
Ascending Colon ◽  
Ascending Colon Cancer

LUNA: A randomized phase II trial of liver resection plus chemotherapy or chemotherapy alone in patients with unresectable lung and resectable liver metastases from colorectal adenocarcinoma.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. TPS3625-TPS3625 ◽  
Author(s):  
Yun Shin Chun ◽  
Reza J. Mehran ◽  
Ching-Wei David Tzeng ◽  
Bryan K. Kee ◽  
A. Dasari ◽  
...  
Keyword(s):  
Overall Survival ◽  
Liver Resection ◽  
Liver Metastases ◽  
Lung Metastases ◽  
Previous Treatment ◽  
Standard Of Care ◽  
Eligibility Criteria ◽  
Liver Remnant ◽  
Response To Chemotherapy ◽  
Low Volume

TPS3625 Background: Liver resection for metastatic colorectal cancer is associated with 5-year overall survival (OS) of 58% and accepted as standard of care. However, the role of liver resection with unresectable low-volume lung metastases is unknown. A recent retrospective study showed that resection of liver metastases was associated with statistically improved OS compared to a matched group of patients treated with systemic therapy alone for lung and liver metastases (3-year OS 43% vs. 14%; Mise Y, Ann Surg Oncol 2015). LUNA is a single-institution phase 2 randomized trial designed to determine the overall survival benefit of liver resection in patients with unresectable lung metastases and to integrate biological surrogates to risk stratify patients and optimize patient selection for hepatectomy. Methods: Eligibility criteria include resectable liver metastases, defined as sufficient liver remnant volume, adequate vascular inflow and outflow, and preservation of 2 contiguous liver segments. Low-volume lung metastases are defined as solid pulmonary nodules < 2 cm in size and < 15 in number. Chest computed tomography is reviewed by an attending thoracic surgeon, and lung metastases are deemed unresectable due to anatomic location, distribution, or patients’ comorbidities. Previous treatment with systemic chemotherapy and/or biologic agents is permitted. After stratification by KRAS status and primary tumor location in the colon vs. rectum, patients are randomized 1:1 to liver resection plus chemotherapy or no liver resection with chemotherapy at the discretion of the treating oncologist as routine standard of care. Patients are restaged every 3‒6 months until 3 years after randomization or death. The primary endpoint is OS. Secondary endpoints include quality of life and identification of biological surrogates in blood and resected liver tissue associated with response to chemotherapy, time to tumor progression, and survival. Targeting an effect size of extending median OS from 17 to 34 months will provide 80% power with 0.05 one-sided alpha with a sample size of 80 patients. Clinical trial information: NCT02738606.

scholarly journals Ascending Colon Cancer Associated with Dermatomyositis Which Was Cured after Colon Resection

2016 ◽  
Vol 10 (2) ◽  
pp. 338-343 ◽  
Author(s):  
Hirohiko Kamiyama ◽  
Koichiro Niwa ◽  
Shun Ishiyama ◽  
Makoto Takahashi ◽  
Yutaka Kojima ◽  
...  
Keyword(s):  
Skin Rash ◽  
Right Hemicolectomy ◽  
Colon Resection ◽  
Ascending Colon ◽  
Cancer Symptoms ◽  
Systemic Inflammatory Disease ◽  
Ascending Colon Cancer ◽  
Additional Therapy ◽  
Symptoms And Signs ◽  
Muscle Ache

A 76-year-old woman with muscle ache, weakness of the extremities, and skin rash was diagnosed with dermatomyositis (DM). Upon the diagnosis of DM, a systemic survey of malignancy revealed an advanced carcinoma of the ascending colon. The patient underwent right hemicolectomy approximately 2 months after the onset of DM. The symptoms and signs of DM disappeared after the surgery without additional therapy. DM is an idiopathic systemic inflammatory disease characterized by muscle ache, muscle weakness, and skin rash. In some cases, DM develops as paraneoplastic syndrome, and it is assumed that 30% of DM patients have cancer. Symptoms and signs of DM can be attenuated by treatment of the malignancy, and they reappear if the malignancy recurs. It is essential to perform a systemic survey of malignancy in DM patients, and treatment of the malignancy has to precede treatment of DM.

scholarly journals Prevention of Delayed Recovery of Right Hemicolectomy in Patients with Ascending Colon Cancer

2020 ◽  
Vol 4 (1) ◽  
pp. 1
Author(s):  
Siti Noviana Sari ◽  
Debie Dahlia
Keyword(s):  
Colon Cancer ◽  
Early Mobilization ◽  
Right Hemicolectomy ◽  
Postoperative Recovery ◽  
Deep Breathing ◽  
Ascending Colon ◽  
Operative Care ◽  
Ascending Colon Cancer ◽  
Delayed Recovery ◽  
Relaxation Exercises

<p class="AbstractContent"><strong>Objective:</strong> This paper aims to analyze perioperative nursing care given to patients with ascending colon cancer who had right hemicolectomy<strong> </strong></p><p class="AbstractContent"><strong>Methods: </strong>Interventions provided in the form of perioperative education, deep breathing relaxation exercises, effective cough exercises, and early postoperative mobilization</p><p class="AbstractContent"><strong>Results:</strong> The results of the evaluation of the implementation of nursing showed the results of patients able to do post-operative exercises in according to education that has been given, the patient was satisfied, and there was no delay post-surgical recovery.<strong></strong></p><p><strong>Conclusion: </strong>Operative education can be used to improve postoperative recovery in colon cancer patients. Some interventions can be made a protocol and applied to improve patient independence, reduce post-operative care days, and increase satisfaction for patients and families.</p><p><strong> </strong></p><p><strong>Keywords: </strong>Colon cancer; deep breathing; early mobilization; effective coughing; preoperative education</p>

Invasive Micropapillary Carcinoma of the Ascending Colon—a Report of a Case

2011 ◽  
Vol 96 (1) ◽  
pp. 82-86 ◽  
Author(s):  
Hajime Shibuya ◽  
Keiji Matsuda ◽  
Ryu Shimada ◽  
Atsushi Horiuchi ◽  
Hisae Iinuma ◽  
...  
Keyword(s):  
Lung Metastases ◽  
Abdominal Cavity ◽  
Right Hemicolectomy ◽  
Tubular Adenocarcinoma ◽  
Invasive Micropapillary Carcinoma ◽  
Ascending Colon ◽  
Micropapillary Carcinoma ◽  
Pathologic Findings ◽  
Diagnostic Work ◽  
Work Up

Abstract Micropapillary carcinoma (MC) has been recently recognized to be a rare but distinctive variant of adenocarcinoma. At present, only a limited number of colorectal MC cases have been reported. We present a case of MC of the ascending colon with distant metastasis. A 61-year-old female patient was hospitalized with a complaint of abdominal pain. A diagnostic work-up revealed cancer of the ascending colon with multiple lung metastases. The patient underwent a right hemicolectomy with lymph node dissection. A peritoneal nodule was observed in the abdominal cavity during surgery, and this nodule was also resected. The pathologic findings of the colon tumor revealed components of conventional tubular adenocarcinoma and micropapillary carcinoma. Lymph nodes and a peritoneal nodule revealed tubular adenocarcinoma. MC is a rare disease but has high malignant potential. In the present case the tumor was small in size, but the patient had a peritoneal and multiple lung metastases.

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