Adrenocortical Carcinoma With Renal Vein Thrombus Extended to Inferior Vena Cava: A Case Report

Adrenocortical carcinoma (ACC) is a rare aggressive tumor. Renal vein and inferior vena cava (IVC) thrombi have been found as uncommon presentations of ACC; however, the implementation of comprehensive therapy has remained controversial in such cases. We report a case of a 46-year-old woman with a large ACC associated with the invasion of tumor to IVC confirmed by imaging and immunohistochemistry examinations. The patient was treated successfully using aggressive surgery, including adrenalectomy and thrombectomy adjunct to an adrenocorticolytic agent. However, she died of metastasis complications at 3-month follow-up period. ACC is a rare malignancy, mostly presenting in advanced stages with poor prognosis. Implementing aggressive surgical therapy might be effective for the management of such cases; however, the short survival duration in our case underscores the need for defining the precise therapy of metastatic ACC associated with venous invasion.

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Functioning Adrenocortical Carcinoma with Extension upto the Right Atrium Producing Cushing's Syndrome

Journal of Clinical Imaging Science ◽

10.4103/2156-7514.116186 ◽

2013 ◽

Vol 3 ◽

pp. 32 ◽

Cited By ~ 2

Author(s):

Santosh Kumar ◽

Gautam R. Choudhary ◽

Arawat Pushkarna

Keyword(s):

Inferior Vena Cava ◽

Cushing’S Syndrome ◽

Adrenocortical Carcinoma ◽

Right Atrium ◽

Inferior Vena ◽

Vena Cava ◽

Cushing's Syndrome ◽

Curative Therapy ◽

Rare Malignancy ◽

The Right

Adrenocortical carcinoma (ACC) is a rare malignancy with poor prognosis. Surgery is the only curative therapy available and overall 5-year survival for patients who undergo a complete resection is 32% to 48%. They are known to produce intravascular invasion and into the inferior vena cava (IVC) and in rare cases they may reach the right atrium. We report a case of functioning ACC extending into the inferior vena cava and right atrium in a female with Cushing's syndrome.

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Adrenocortical carcinoma with inferior vena cava, left renal vein and right atrium tumor thrombus extension

International Journal of Surgery Case Reports ◽

10.1016/j.ijscr.2015.07.008 ◽

2015 ◽

Vol 15 ◽

pp. 137-139 ◽

Cited By ~ 7

Author(s):

Pronio Annamaria ◽

Piroli Silvia ◽

Ciamberlano Bernardo ◽

De Luca Alessandro ◽

Marullo Antonino ◽

...

Keyword(s):

Inferior Vena Cava ◽

Adrenocortical Carcinoma ◽

Right Atrium ◽

Renal Vein ◽

Tumor Thrombus ◽

Inferior Vena ◽

Left Renal Vein ◽

Vena Cava

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Thrombosed interrupted inferior vena cava and retroaortic left renal vein mimicking retroperitoneal neoplasm

Abdominal Imaging ◽

10.1007/s00261-006-9052-9 ◽

2006 ◽

Vol 32 (3) ◽

pp. 403-406 ◽

Cited By ~ 10

Author(s):

Sevdenur Cizginer ◽

Servet Tatli ◽

Jeffrey Girshman ◽

Joshua A. Beckman ◽

Stuart G. Silverman

Keyword(s):

Inferior Vena Cava ◽

Renal Vein ◽

Inferior Vena ◽

Left Renal Vein ◽

Vena Cava ◽

Retroperitoneal Neoplasm

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Prevalence of Congenital Anomalies of the Inferior Vena Cava: CT Assessment in Thai Patients

Journal of the Medical Association of Thailand ◽

10.35755/jmedassocthai.2021.09.12629 ◽

2021 ◽

Vol 104 (9) ◽

pp. 1459-1464

Keyword(s):

Inferior Vena Cava ◽

Renal Vein ◽

Inferior Vena ◽

Left Renal Vein ◽

Vena Cava ◽

Renal Veins ◽

Retrocaval Ureter ◽

Radiology Reports ◽

Contrast Enhanced ◽

Study Population

Objective: To determine the prevalence of inferior vena cava (IVC) anomalies in Thai patients who underwent contrast-enhanced computed tomography (CT) of the abdomen. Materials and Methods: Two radiologists retrospectively and independently reviewed the contrast-enhanced abdominal CT examinations in 1,429 Thai patients between August 1, 2018 and January 25, 2019 who met the inclusion criteria. Patients were included, if (a) their CT showed well visualized IVC, renal veins, and right ureter that were not obliterated by tumor, cyst, fluid collection, or intraperitoneal free fluid, (b) they had not undergone previous abdominal surgery that altered anatomical configuration of the IVC, renal veins, and right ureter. The presence of all IVC anomalies were recorded. Results: Among the 1,429 studied patients, 678 were male (47.4%) and 751 were female (52.6%). The prevalence of IVC anomalies was 3.5%. Five types of IVC anomalies were presented. The most common was circumaortic left renal vein in 24 patients or 48.0% of all IVC anomalies and 1.7% of the study population, followed by retroaortic left renal vein in 15 patients or 30.0 % of all IVC anomalies and 1.0% of the study population. Other IVC anomalies included double IVC, left IVC, and retrocaval ureter at 0.5%, 0.2%, and 0.1% of the study population, respectively. Conclusion: The prevalence of IVC anomalies in the present study differed from the previous studies conducted in other countries, which may be attributable to differences in race and ethnicity. Awareness of these anomalies is essential when evaluating routine CT examinations in asymptomatic patients. Their presence should be carefully noted in radiology reports to avoid anomaly-related complications. Keywords: Prevalence; IVC anomalies; Circumaortic left renal vein; Retroaortic left renal vein; Double IVC; Left IVC; Retrocaval ureter

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Renal primitive neuroectodermal tumour: Case series and brief review

Canadian Urological Association Journal ◽

10.5489/cuaj.1770 ◽

2014 ◽

Vol 8 (3-4) ◽

pp. 241

Author(s):

Tadeusz Kroczak ◽

Rajan Sharda ◽

Darrel Drachenberg ◽

Turki Al-Essawi

Keyword(s):

Literature Review ◽

Inferior Vena Cava ◽

Primitive Neuroectodermal Tumor ◽

Inferior Vena ◽

Vena Cava ◽

Case Series ◽

Primitive Neuroectodermal Tumour ◽

Pathologic Features ◽

Rare Malignancy ◽

Pathologic Analysis

Renal primitive neuroectodermal tumor is a rare malignancy. These tumours rarely present with caval involvement. We report 2 cases of primitive neuroectodermal tumours (PNETs) with inferior vena cava involvement. The initial presentation and outcomes differed significantly. The diagnosis was confirmed using histologic and pathologic analysis. We present a brief literature review and an outline of typical clinical and pathologic features of renal PNETs.

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