silicon fluoride
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scholarly journals Recent Advances in the Clinical Translation of Silicon Fluoride Acceptor (SiFA) 18F-Radiopharmaceuticals

2021 ◽  
Vol 14 (7) ◽  
pp. 701
Author(s):  
Lexi Gower-Fry ◽  
Travis Kronemann ◽  
Andreas Dorian ◽  
Yinglan Pu ◽  
Carolin Jaworski ◽  
...  
Keyword(s):  
Medical Imaging ◽  
Small Molecules ◽  
Isotopic Exchange ◽  
Clinical Translation ◽  
Clinical Use ◽  
Labeled Compounds ◽  
Biologically Relevant ◽  
Clinical Applicability ◽  
Silicon Fluoride

The incorporation of silicon fluoride acceptor (SiFA) moieties into a variety of molecules, such as peptides, proteins and biologically relevant small molecules, has improved the generation of 18F-radiopharmaceuticals for medical imaging. The efficient isotopic exchange radiofluorination process, in combination with the enhanced [18F]SiFA in vivo stability, make it a suitable strategy for fluorine-18 incorporation. This review will highlight the clinical applicability of [18F]SiFA-labeled compounds and discuss the significant radiotracers currently in clinical use.

scholarly journals Development of silicon fluoride acceptor (SiFA)-conjugated antibodies targeting TREM2 and Poly-GA repeats as new tracers for PET imaging of neurodegenerative diseases

2021 ◽  
Vol 96-97 ◽  
pp. S37
Author(s):  
Monireh Shojaei ◽  
Christian Haass ◽  
Dieter Edbauer ◽  
Kai Schlepckow ◽  
Peter Bartenstein ◽  
...  
Keyword(s):  
Neurodegenerative Diseases ◽  
Pet Imaging ◽  
Silicon Fluoride

Rapid One-Step 18F-Labeling of Peptides via Heteroaromatic Silicon-Fluoride Acceptors

2020 ◽  
Vol 22 (3) ◽  
pp. 804-808 ◽  
Author(s):  
Maruthi Kumar Narayanam ◽  
Anton A. Toutov ◽  
Jennifer M. Murphy
Keyword(s):  
One Step ◽  
Silicon Fluoride

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor (SiFA) for Positron Emission Tomography

10.3791/60623 ◽  
2020 ◽  
Author(s):  
David Connolly ◽  
Justin J. Bailey ◽  
Harun Ilhan ◽  
Peter Bartenstein ◽  
Carmen Wängler ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Emission Tomography ◽  
Positron Emission ◽  
Silicon Fluoride

scholarly journals The 4-N-acyl and 4-N-alkyl gemcitabine analogues with silicon-fluoride-acceptor: Application to 18F-Radiolabeling

2018 ◽  
Vol 148 ◽  
pp. 314-324 ◽  
Author(s):  
Cesar Gonzalez ◽  
Andersson Sanchez ◽  
Jeffrey Collins ◽  
Ksenia Lisova ◽  
Jason T. Lee ◽  
...  
Keyword(s):  
Silicon Fluoride

Silicon Fluoride Acceptors (SiFAs) for Peptide and Protein Labeling with18F

2015 ◽  
pp. 149-161 ◽  
Author(s):  
Ralf Schirrmacher ◽  
Alexey Kostikov ◽  
Carmen Wängler ◽  
Klaus Jurkschat ◽  
Vadim Bernard-Gauthier ◽  
...  
Keyword(s):  
Protein Labeling ◽  
Silicon Fluoride

Luminescent and thermal properties of a novel red-emitting silicon fluoride acrylate-Eu(III) copolymer for white LEDs

2014 ◽  
Vol 147 (3) ◽  
pp. 777-782 ◽  
Author(s):  
Jun Hu ◽  
Lin Xu ◽  
Lei Xu ◽  
Taiju Tsuboi ◽  
Wei Huang ◽  
...  
Keyword(s):  
Thermal Properties ◽  
White Leds ◽  
Silicon Fluoride
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