Chapter 10 examines radiologic images for common and uncommon pediatric airway and mediastinal disorders. These include pediatric airway disorders such as epiglottitis, croup, exudative tracheitis, congenital tracheomalacia, obstructive sleep apnea, retropharyngeal abscess, esophageal atresia, and tracheoesophageal fistula. The chapter goes on to look at vascular impressions on the trachea and esophagus, including double aortic arch, aberrant right subclavian artery, right aortic arch with aberrant left subclavian artery, pulmonary sling, esophageal and tracheal foreign bodies, and bronchial foreign body. Mediastinal abnormalities examined include normal thymus and mediastinal masses. The chapter covers the clinical features and anatomy associated with these disorders as well as their diagnosis based on the radiologic imaging.