A rare case of peripheral giant cell granuloma

Peripheral Giant Cell Granuloma or the so called “Giant Cell Epulis” is the most common oral giant cell lesion. It is described as non-neoplastic, hyperplastic lesion occurring exclusively on gingival/alveolar crest that appears as a overgrowth of tissues, following trauma or irritation arising from periosteum or periodontal membrane. It can be sessile or pedunculated with size usually less than 2cm. Although being uncommon, this lesion carries a lot of uncertainity in terms of its etiology, growth potential, biological behavior (recurrence), histogenesis of its cells and its treatment. We hereby report a case of a 49-year old male patient, with peripheral giant cell granuloma in mandibular posterior region, who was successfully treated and is on regular follow up since 6 months.

Resection and Reconstruction is the Procedure of Choice for Giant Cell Lesions of Small Bones: A Case Report and Literature Review

Background: Giant cell lesion of small bones (GCLSB), also known as giant cell reparative granuloma, is a rare tumor-like condition occurring in the small bones of the hands and feet. GCLSB lacks specific clinical, radiological, and histological manifestations. There are no standardized protocols for treatment. Case presentation: Here, we report a 16-year-old male with recurrent GCLSB in the proximal phalanx of the left thumb. The lesion was successfully resected with bone grafting. Conclusions: We summarized the characteristics of 33 reported cases of GCLSB from 1983 to date, including gender, age, lesion sites, recurrence, and treatment. We conclude that resection and reconstruction with curettage is the treatment of choice.

Dental Management of Peripheral Giant Cell Granuloma in an 8-Year-Old Boy: A Case Report

Background: Peripheral giant cell granuloma (PGCG) or the so-called giant cell epulis is the most common oral giant cell lesion. It normally appears as a soft tissue purple-red nodule. This lesion is certainly not a true neoplasm, but in nature, it may be reactive, thought to be stimulated by local irritation or trauma. Nonetheless, the exact cause is definitely not understood well. In appearance, lesions vary from smooth, uniformly outlined masses to irregularly developed, multilobed surface indentation protuberances. Margin ulcerations are occasionally observed as well. The lesions are painless, differ in size, and can cover many teeth. It may be a lesion on the gingiva or alveolar crest that is sessile or pedunculated, common with respect to the molars and incisors and occurs in reaction to the local response.