Beginning in the 1840s, Anglo-French gunboat diplomacy and “unequal treaties” forcibly opened China to European economic interests and, in so doing, introduced unprecedented opportunities for Christian expansion. Catholic missionaries and priests returned to nurture “Old Catholics” and plant new missions, and for the first time Protestants appeared on the scene with millennial hopes of reaching “China’s millions.” This chapter begins by giving general attention to reasons for the Chinese to reject or accept the Christian message. It then turns to specific discussions of the Taiping Heavenly Kingdom, the China Inland Mission, “Pastor Xi” (Xi Liaozhi), and first-generation Fuzhou Protestants. It concludes with an examination of the views of American theological liberals who, beginning in the late nineteenth century, rejected the traditional Christian emphasis on the necessity of conversion.