In the fifty-eighth chapter of Isaiah, the Hebrew prophet exhorts the reader to transcend rote ritualism and engage directly in service to the poor, the suffering, and the oppressed. In exhorting his allies to do likewise, abolitionist William Lloyd Garrison drew on this language frequently, most canonically in his 1833 “Declaration of the National Anti-Slavery Convention” and his 1859 “Eulogy for John Brown.” In the generation in between, something extraordinary happened: the goal of ending slavery completely lurched from the cultural margins to the center. Inspired by this precedent, this chapter explores some of the extraordinary religious organizing taking place in the trenches under the banner of prison abolition, from Protestants and Catholics, to Muslims and Jews, to those who are spiritual but not religious.