defective incorporation
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2020 ◽  
Author(s):  
Aakarsh Banyal ◽  
Atmaram Shelke

Abstract Speciesism is a bias that causes humans to accord themselves moral superiority in their dealings with non-humans. When speciesism permeates legislative thought, it leads to statutes that sacrifice the interests of non-humans to those of humans. The Prevention of Cruelty to Animals Act, 1960 (‘PCA Act’) is no exception. Section 11 of this Act enumerates specific instances that qualify as animal cruelty and prescribes punishment for the same. However, this section is riddled with statutory flaws, some owing their origin to speciesism: inadequate and sweeping punishments, the defective incorporation of the ‘Doctrine of Necessity’, and the limited recognition of cruel acts. This article seeks to analyse each of the aforementioned faults and prescribe solutions which would strengthen the animal welfare regime as a whole. While stressing on broadening the scope of punishable acts under section 11, along with the need for statutory language to reflect ‘severity’ of punishment, the article also argues for differentiated punishment drawn from a consequence-based model which acknowledges the trauma and suffering of the animal. The intention is to prompt a discourse on the ideal drafting of animal welfare legislation.


PEDIATRICS ◽  
1986 ◽  
Vol 78 (1) ◽  
pp. 51-54
Author(s):  
David S. Rosenblatt ◽  
Rachel Laframboise ◽  
Jeanne Pichette ◽  
Pierre Langevin ◽  
Bernard A. Cooper ◽  
...  

An infant with vitamin B12-responsive methylmalonic aciduria and no homocystinuria or megaloblastic anemia presented with stomatitis, glossitis, convulsions, and developmental delay. Cultured fibroblasts showed defective incorporation of both [14C]5-methyltetrahydrofolate and [14C]propionate into protein by whole cells and a decrease of methionine synthase activity in cell extracts. Despite excessive incorporation of [57Co]cyano-B12 by fibroblasts from the patient, free vitamin B12 was unable to efflux from lysosomes, and, therefore, synthesis of both adenosyl-B12 and methyl-B12 was impaired.


1977 ◽  
Vol 120 (3) ◽  
pp. 507-515 ◽  
Author(s):  
Seymour Greenfield ◽  
Steven Brostoff ◽  
Edward Hogan

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