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SAR-Guided Scoring Function and Mutational Validation Reveal the Binding Mode of CGS-8216 at the α1+/γ2– Benzodiazepine Site

2018 ◽  
Vol 58 (8) ◽  
pp. 1682-1696 ◽  
Author(s):  
David C. B. Siebert ◽  
Marcus Wieder ◽  
Lydia Schlener ◽  
Petra Scholze ◽  
Stefan Boresch ◽  
...  
Keyword(s):  
Scoring Function ◽  
Binding Mode ◽  
Cgs 8216 ◽  
Benzodiazepine Site

The benzodiazepine antagonist CGS 8216 prevents hyperammonemia-induced somatostatin receptor reduction in the brain

1995 ◽  
Vol 688 (1-2) ◽  
pp. 1-7
Author(s):  
María del Carmen Boyano-Adánez ◽  
Guillermo Bodega ◽  
Ángela Martín-Espinosa ◽  
Eduardo Arilla
Keyword(s):  
Somatostatin Receptor ◽  
Benzodiazepine Antagonist ◽  
Cgs 8216 ◽  
The Brain

Food palatability and hunger modulated effects of CGS 9896 and CGS 8216 on food intake

1995 ◽  
Vol 51 (2-3) ◽  
pp. 499-503 ◽  
Author(s):  
Shu-Wen Chen ◽  
M.Frances Davies ◽  
Gilda H Loew
Keyword(s):  
Food Intake ◽  
Cgs 9896 ◽  
Cgs 8216

Lack of effect of flumazenil and CGS 8216 on the anxiolytic-like properties of loreclezole

1994 ◽  
Vol 252 (3) ◽  
pp. 325-328 ◽  
Author(s):  
Gerard R. Dawson ◽  
Rachel Curnow ◽  
Peter Bayley ◽  
Adam Rambridge ◽  
Mark D. Tricklebank
Keyword(s):  
Cgs 8216
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