Rh(I)-Catalyzed Enantioselective Cyclization of Enyne through Site-Selective C(sp3)-H Bond Activation Triggered by Formation of Rhodacycle

Rh(I)-catalyzed enantioselective cyclization of enyne through C(sp3)-H bond activation was investigated. It was found that the cyclization of enyne having a t-butyl moiety on the alkene afforded a spirocyclic compound (up to 92% ee), while the cyclization of enyne having an i-propyl or an ethyl group on the alkene gave a cyclic diene (up to 98% ee). Furthermore, an intermolecular competition reaction using a deuterium-labeled substrate revealed that C(sp3)-H bond activation was one of the key steps, having a high energy barrier, in this cyclization.

Correction: Rapid kinetic evaluation of homogeneous single-site metallocene catalysts and cyclic diene: how do the catalytic activity, molecular weight, and diene incorporation rate of olefins affect each other?

Correction for ‘Rapid kinetic evaluation of homogeneous single-site metallocene catalysts and cyclic diene: how do the catalytic activity, molecular weight, and diene incorporation rate of olefins affect each other?’ by Amjad Ali et al., RSC Adv., 2021, 11, 31817–31826, DOI: 10.1039/D1RA06243C.

Rapid kinetic evaluation of homogeneous single-site metallocene catalysts and cyclic diene: how do the catalytic activity, molecular weight, and diene incorporation rate of olefins affect each other?

The kinetics and mechanism of ethylene and 5-ethylidene-2-norbornene copolymerization catalyzed by rac-Et(Ind)2ZrCl2 were investigated using 2-thiophenecarbonyl chloride.