scorpion neurotoxin
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2019 ◽  
Vol 20 (14) ◽  
pp. 3467 ◽  
Author(s):  
Sheng-Qun Deng ◽  
Jia-Ting Chen ◽  
Wen-Wen Li ◽  
Min Chen ◽  
Hong-Juan Peng

Androctonus australis Hector insect toxin (AaIT), an insect-selective toxin, was identified in the venom of the scorpion Androctonus australis. The exclusive and specific target of the toxin is the voltage-gated sodium channels of the insect, resulting in fast excitatory paralysis and even death. Because of its strict toxic selectivity and high bioactivity, AaIT has been widely used in experiments exploring pest bio-control. Recombinant expression of AaIT in a baculovirus or a fungus can increase their virulence to insect pests and diseases vectors. Likewise, transgenic plants expressing AaIT have notable anti-insect activity. AaIT is an efficient toxin and has great potential to be used in the development of commercial insecticides.



AMB Express ◽  
2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Sheng-Qun Deng ◽  
Qun-Di Cai ◽  
Ming-Zhi Deng ◽  
Qiang Huang ◽  
Hong-Juan Peng


2015 ◽  
Vol 37 (10) ◽  
pp. 1929-1936 ◽  
Author(s):  
Yuejun Fu ◽  
Xing Li ◽  
Jun Du ◽  
Shuhua Zheng ◽  
Aihua Liang
Keyword(s):  


2014 ◽  
Vol 289 (20) ◽  
pp. 14331-14340 ◽  
Author(s):  
Antonina A. Berkut ◽  
Dinara R. Usmanova ◽  
Steve Peigneur ◽  
Peter B. Oparin ◽  
Konstantin S. Mineev ◽  
...  


Toxicon ◽  
2012 ◽  
Vol 60 (2) ◽  
pp. 185
Author(s):  
Kenya Hernández-Salgado ◽  
Lourival D. Possani ◽  
Gerardo Corzo
Keyword(s):  


2010 ◽  
Vol 98 (3) ◽  
pp. 110a
Author(s):  
Z Takacs ◽  
M Toups ◽  
A Kollewe ◽  
E Johnson ◽  
L.G. Cuello ◽  
...  


2009 ◽  
Vol 106 (52) ◽  
pp. 22211-22216 ◽  
Author(s):  
Zoltan Takacs ◽  
Megan Toups ◽  
Astrid Kollewe ◽  
Erik Johnson ◽  
Luis G. Cuello ◽  
...  


2009 ◽  
Vol 22 (2) ◽  
pp. 179-186 ◽  
Author(s):  
HERVÉ DARBON ◽  
EMMANUEL JOVER ◽  
FRANÇOIS COURAUD ◽  
HERVÉ ROCHAT


2008 ◽  
Vol 81 (3) ◽  
pp. 515-522 ◽  
Author(s):  
Dingding Lu ◽  
Monica Pava-Ripoll ◽  
Zengzhi Li ◽  
Chengshu Wang


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