scholarly journals Application of the Scorpion Neurotoxin AaIT against Insect Pests

2019 ◽  
Vol 20 (14) ◽  
pp. 3467 ◽  
Author(s):  
Sheng-Qun Deng ◽  
Jia-Ting Chen ◽  
Wen-Wen Li ◽  
Min Chen ◽  
Hong-Juan Peng
Keyword(s):  
Transgenic Plants ◽  
Sodium Channels ◽  
Insect Pests ◽  
Recombinant Expression ◽  
Voltage Gated ◽  
Pests And Diseases ◽  
Voltage Gated Sodium Channels ◽  
Scorpion Neurotoxin ◽  
Insect Toxin ◽  
Insect Activity

Androctonus australis Hector insect toxin (AaIT), an insect-selective toxin, was identified in the venom of the scorpion Androctonus australis. The exclusive and specific target of the toxin is the voltage-gated sodium channels of the insect, resulting in fast excitatory paralysis and even death. Because of its strict toxic selectivity and high bioactivity, AaIT has been widely used in experiments exploring pest bio-control. Recombinant expression of AaIT in a baculovirus or a fungus can increase their virulence to insect pests and diseases vectors. Likewise, transgenic plants expressing AaIT have notable anti-insect activity. AaIT is an efficient toxin and has great potential to be used in the development of commercial insecticides.

scholarly journals Erratum to: Voltage-gated Sodium Channels and Blockers: An Overview and Where Will They Go?

2020 ◽  
Author(s):  
Zhi-mei Li ◽  
Li-xia Chen ◽  
Hua Li
Keyword(s):  
Open Access ◽  
Sodium Channels ◽  
Voltage Gated ◽  
Internet Portal ◽  
Creative Commons ◽  
Link Type ◽  
Voltage Gated Sodium Channels

The article “Voltage-gated Sodium Channels and Blockers: An Overview and Where Will They Go?”, written by Zhi-mei LI, Li-xia CHEN, Hua LI, was originally published electronically on the publisher’s internet portal on December 2019 without open access. With the author(s)’ decision to opt for Open Choice, the copyright of the article is changed to © The Author(s) 2020 and the article is forthwith distributed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The original article has been corrected.Corresponding authors: Li-xia CHEN, Hua LI

scholarly journals μ‐Conotoxin KIIIA peptidomimetics that block human voltage‐gated sodium channels

2020 ◽  
Author(s):  
Astrid Knuhtsen ◽  
Rachel Whiting ◽  
Fergus S. McWhinnie ◽  
Charlotte Whitmore ◽  
Brian O. Smith ◽  
...  
Keyword(s):  
Sodium Channels ◽  
Voltage Gated ◽  
Voltage Gated Sodium Channels
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