Dealing with the biological data, the skewed distribution is approximated by the Log-Normal Regression model (LNRM). Traditional estimation techniques for the LNRM are sensitive to unusual observations. These observations greatly affect the model analysis, which makes imprecise conclusions. To overcome this issue, we proposed to develop diagnostics measures based on local influence diagnostics to identify such curious observations in the LNRM under censoring. The proposed measures are derived by perturbing the case weight, response, and explanatory variables. Furthermore, we also consider the One-Step Newton-Raphson method and generalized cook’s distance. We study the Monte Carlo simulation and its application to real data to illustrate the developed approaches.