Morbidity with malignant neoplasms of female genital organs in Amur region

Morbidity with malignant neoplasms offemale genital organs in Amur region makes up 38-45per 100000 women. Cervical and uterine carcinomae dominate through all malignant tumors. The authors point to the low rate оfcase detecting as to women with genital neoplasms. Late diagnostics lead to unfavourable prognosis. General cancer mortality decreased for the last three years but still remains high. To reduce the rate of oncological diseases a regional programme including tumor and pretumor screening is to be elaborated.

The Importance of Vaccination Against HPV

The human papillomavirus is a DNA virus that is involved in the pathogenesis of several benign and malignant lesions. Although numerous types of HPV exist, vaccines currently target HPV’s 6, 11, 16, and 18, which are the most commonly implicated in verrucae and oral-genital neoplasms. Although the HPV vaccine has been recommended as part of the vaccination schedule in adolescents for several years, widespread inoculation has not yet become common practice. It is imperative that vaccination be more broadly instituted to decrease the incidence of HPV related lesions in both males and females

Multiple Primary Neoplasms in the Western Hospital Region, Scotland: A Survey Based on Cancer Registration Data

A study of multiple primary neoplasms in the Western Hospital Region of Scotland {which covers about 3,000,000 inhabitants) has been carried out, using cancer registration data, for the period July 1958–66. The total registrations were 61,288. (1) After elimination of doubtful cases, 428 cases of multiple primary neoplasms remained for study, 0.73 per cent of the sample. (2) Multiple primaries occurred most commonly in people in whom the first malignant lesion appeared late in life. (3) In only a few sites did the relative prevalence of cancers in the multiple primaries (M.P.) series differ from that in the single primaries (S.P.) series. The incidence of bilateral breast cancer was less than 1 per cent. This figure is much lower than those reported by other workers. About half were cases of ‘simultaneous’ bilateral breast cancer, and of the others, about one quarter occurred within one year of discovery of the first neoplasm. Genital neoplasms were very common in the female M.P. series (40%), but in males, the M.P. and S.P. series showed identical prevalence of genital neoplasms. (4) Associations between pairs of cancers sufficiently pronounced to be statistically significant were few, occurring in 4 pairs of sites in males and in 5 in females. Skin cancers featured in all male and 2 of the female pairings, and genital cancers in three female pairings. (5) There was a very marked likelihood for cancers of the larynx, uterus (all types), bladder and skin to be the first primary to appear (70% of cases or over). (6) Almost one third of second primaries occurred within a year of the first and after this the number declined rapidly. This held good when the figures were related to the number of survivors and to the number of survival-months.