A 13 year hospital based study on the Trend of Urinary Stone Disease in Uttarakhand, India

Background: The present retrospective study on urinary stone disease in the Uttarakhand state was necessitated as no study has been done yet. Methods: A retrospective study covering a period of about 13 years (2005-18) was conducted on the urinary stones removed from the patients, admitted at Himalayan Institute of Medical Sciences, Dehradun. The incidence of the disease, site of stones in urinary tract upon diagnosis, composition of removed stones and occurrence of a possible co-relationship between the incidence of the urinary stone disease at different times, age, sex, religion of the patients was investigated. Results: The frequency of occurrence of urinary stones in males was found to be almost three times more as compared to their female counterparts. The above trend was consistent over the entire period of the study. Interestingly, in the Muslim and Sikh population of the area, females were found to be less prone to the problem as compared to their Hindu counterparts. However, in all religious groups, 21-40 years old subjects were found to be most susceptible to the problem and approximately 90% of the urinary stones were recovered from the kidneys and primarily composed of calcium oxalate. Conclusion: The co-relationship between the occurrence of urinary stones with age, sex of the patients, their religion & site of stones on diagnosis was found to be statistically significant. Keywords: Urolithiasis, Urinary Stone disease, Urinary calculus, Renal stones.

The influence of natural mineral water on the structural and functional changes in the rat kidneys under urolithiasis modelling

In the experiment on the white Wistar rats, the authors evaluated kidneys changes in urolithiasis modelling (Kidney stone disease, KSD) and the possibility of correcting these changes by internal use of the mineral water (MW) with high organic matter content. The results of the studies revealed structural pathological changes in the kidneys in the form of changes of the part of glomeruli capillaries and gross changes in the kidneys tubules and interstitial layers. At the same time, the functional kidneys activity is manifested in the form of increased urination and a significant increase in urination. Urine metabolic characteristics are also change. The use of MW leads to an improvement in the capillaries of the renal corpuscles structure and almost complete restoration of the tubules structure. The functional activity of the kidneys and the quality of urine have significantly improving. The authors believe that the organic compounds of MW, which mainly determine its biological activity, contribute to the improvement of the regulation of metabolic processes and, accordingly, have a positive effect on the structural and functional parameters of the kidneys.. Keywords: urolithiasis, structural and functional characteristics of the kidneys, mineral water,

A DIETA COMO UM FATOR DE PREVENÇÃO E TRATAMENTO DE UROLITÍASE EM CÃES E GATOS

The urolithiasis is one of the most motives of dogs and cats complaints attended with urinary affections. Objective of the work was to show the importance of the diet with a factor of prevention and treatment of urolithiasis in dogs and cats. The research technique used was bibliographic research. The formation of kidney crystals and stones with causes as decreased urination associated with urine supersaturation, being able to be related to dietary factors. Amoung the main existings uroliths, stand out those made of struvite and calcium oxalate. The nutrition can be related to the formation, prevention and treatment of urolithiasis, mainly in relation to the pH control and acid/basic balance present in industrialized rations. Given the above, the research presents information that shows the interference of nutrition in dogs and cats with urolithiasis. Keywords: Urolithiasis. Struvite. Calcium oxalate. Diet.