A DIETA COMO UM FATOR DE PREVENÇÃO E TRATAMENTO DE UROLITÍASE EM CÃES E GATOS

2020 ◽  
Vol 03 (01) ◽  
pp. 71-78
Author(s):  
Hadrian Pancini ◽  
Keyword(s):  
Calcium Oxalate ◽  
Ph Control ◽  
Dietary Factors ◽  
Research Technique ◽  
Prevention And Treatment ◽  
Treatment Of Urolithiasis ◽  
Keywords Urolithiasis

The urolithiasis is one of the most motives of dogs and cats complaints attended with urinary affections. Objective of the work was to show the importance of the diet with a factor of prevention and treatment of urolithiasis in dogs and cats. The research technique used was bibliographic research. The formation of kidney crystals and stones with causes as decreased urination associated with urine supersaturation, being able to be related to dietary factors. Amoung the main existings uroliths, stand out those made of struvite and calcium oxalate. The nutrition can be related to the formation, prevention and treatment of urolithiasis, mainly in relation to the pH control and acid/basic balance present in industrialized rations. Given the above, the research presents information that shows the interference of nutrition in dogs and cats with urolithiasis. Keywords: Urolithiasis. Struvite. Calcium oxalate. Diet.

scholarly journals Urolithiasis in male patients: A pilot study on the ethnic differences and clinical profile

2014 ◽  
Vol 4 (4) ◽  
pp. 393-98
Author(s):  
Jayadevan Sreedharan ◽  
LJ John ◽  
HAM Aly Freeg ◽  
J Muttappallymyalil
Keyword(s):  
Uric Acid ◽  
Calcium Oxalate ◽  
Calcium Oxalate Monohydrate ◽  
Dietary Factors ◽  
Clinical Profile ◽  
Urinary Stones ◽  
Ureteral Stones ◽  
Stone Size ◽  
Uric Acid Stones ◽  
Male Patients

Background   Ethnicity play a role in the occurrence of urinary stones, probably related to climatic, environmental and dietary factors in ethnic groups. The association between ethnicity, age, clinical profile, stone size with type of ureteric stones among males with urolithiasis was studied.   Materials and Methods Male patients (>18 years) with lower ureteral stones size <10mm attending outpatient department of Urology, at a private hospital, Ajman over a period of one year were included. Ethics approval was obtained from Institutional Ethics Committee. Data was retrieved from the case records which included socio-demographic variables (age, ethnicity), clinical profile (ureteric colic, duration of pain, other complaints), and laboratory investigations (type of stone, stone size). Descriptive and inferential statistics were performed with SPSS-20 and p values <0.05 considered significant. Results 185 male patients were included. Mean age was 41.5 (7.3) years, range (22-71) years. Out of the total, 81 (43.8%) patients were Asians, 81(43.8%) Arabs and 23 (12.4%) were of other ethnicity. Most patients (95.1%) presented with ureteric pain. 49 (26.5%) had family history of stone disease where calcium oxalate monohydrate and uric acid stones were common, with majority being first degree relation. Data on stone type was available for 90 patients; of which, 21 were calcium oxalate monohydrate, 33-calcium oxalate dehydrate, 24-uric acid and remaining 12 other form of stones. Average age for different types of stone was 38.3, 41.6, 39.4 and 42.8 years for calcium oxalate monohydrate, calcium oxalate dehydrate, uric acid and other types respectively. Conclusion Uric acid stones were more prevalent among Asians and calcium oxalate-dehydrate stones among Arabs. Future studies can be conducted among multiethnic population focusing on dietary pattern and stone analysis.DOI: http://dx.doi.org/10.3126/nje.v4i4.11359 Nepal Journal of Epidemiology 2014; 4(4):393-98

scholarly journals The Multifaceted Roles of Diet, Microbes, and Metabolites in Cancer

Cancers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 767
Author(s):  
Heather Armstrong ◽  
Michael Bording-Jorgensen ◽  
Eytan Wine
Keyword(s):  
Human Health ◽  
Chemical Compounds ◽  
Dietary Factors ◽  
Cancer Development ◽  
Future Research ◽  
Preventative Medicine ◽  
Prevention And Treatment ◽  
The Relationship ◽  
Common Misconceptions

Many studies performed to date have implicated select microbes and dietary factors in a variety of cancers, yet the complexity of both these diseases and the relationship between these factors has limited the ability to translate findings into therapies and preventative guidelines. Here we begin by discussing recently published studies relating to dietary factors, such as vitamins and chemical compounds used as ingredients, and their contribution to cancer development. We further review recent studies, which display evidence of the microbial-diet interaction in the context of cancer. The field continues to advance our understanding of the development of select cancers and how dietary factors are related to the development, prevention, and treatment of these cancers. Finally, we highlight the science available in the discussion of common misconceptions with regards to cancer and diet. We conclude this review with thoughts on where we believe future research should focus in order to provide the greatest impact towards human health and preventative medicine.

scholarly journals Effect of Hard Water on the Prevention and Treatment of Calcium Oxalate Nephrolithiasis in Rats

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Mousa Al-Reza Hadjzadeh ◽  
Parichehr Hayatdavoudi ◽  
Reza Karim Keshteh ◽  
Nazanin Entezari Entezari ◽  
Roghayeh Pakdel ◽  
...  
Keyword(s):  
Drinking Water ◽  
Ethylene Glycol ◽  
Calcium Oxalate ◽  
Wistar Rats ◽  
Hard Water ◽  
Control Group ◽  
Treatment Groups ◽  
High Calcium ◽  
Prevention And Treatment ◽  
Male Wistar Rats

Background: There is a folk belief that drinking Ramsar spring mineral water (RSW) is a remedy for renal stones. Objectives: This study aimed to evaluate the effect of RSW on prevention or treatment of nephrolithiasis in male Wistar rats and identify the constituents of the water. Methods: Nephrolithiasis was induced by providing drinking water containing 1% ethylene glycol (EG) for two weeks in male Wistar rats. The animals were divided into prevention and treatment groups, each contained five sub-groups (10 rats for each). Prevention groups were treated for two weeks: control group (without treatment), EG group (1% ethylene glycol in drinking water), RSW 5, 10, and 15% groups (1% ethylene glycol + RSW 5, 10, and 15% in drinking water). The treatment groups received 1% EG for two weeks, then it was discontinued, and the RSW (10, 15, and 20%) was added to the drinking water for the next two weeks. The calcium oxalate (CaOx) depositions in the kidneys' tubules were evaluated by Hematoxylin and Eosin staining. The spring water was analyzed for its constituents. Results: Calcium oxalate crystals were significantly increased in EG group as compared to the control group (P < 0.05). Moreover, RSW did not significantly prevent CaOx crystals but alleviated CaOx crystals at 15 and 20% concentrations in the treatment protocol (P < 0.001). Conclusions: The hard water of Ramsar spring reduced CaOx crystals in nephrolithiatic rats, which may be due to its high calcium and magnesium content.

scholarly journals Association of Urine Findings with Metabolic Syndrome Traits in a Population of Patients with Nephrolithiasis

2021 ◽  
Author(s):  
Virginia L Hood ◽  
Kevan M Sternberg ◽  
Desiree de Waal ◽  
John R Asplin ◽  
Carley Mulligan ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Uric Acid ◽  
Calcium Oxalate ◽  
Protein Intake ◽  
Dietary Factors ◽  
Acid Excretion ◽  
Urine Ph ◽  
Stone Composition ◽  
Calcium Oxalate Stones ◽  
Net Acid Excretion

Background and objectives: The odds of nephrolithiasis increase with more metabolic syndrome (met-s) traits. We evaluated associations of metabolic and dietary factors from urine studies and stone composition with met-s traits in a large cohort of stone-forming patients. Design, setting, participants & measurements: Patients >18 years, who were evaluated for stones with 24 h urine collections, July 2009-December 2018, had records reviewed retrospectively. Patient factors, laboratory values and diagnoses were identified within 6 months of urine collection and stone composition within 1 year. Four groups with 0, 1, 2, > 3 met-s traits (hypertension, obesity, dyslipidemia, diabetes) were evaluated. Trends across groups were tested using linear contrasts in analysis of variance and analysis of covariance. Results: 1473 patients met inclusion criteria (835 with stone composition). Met-s groups were 0=684, 1=425, 2=211, 3 and 4 =153. There were no differences among groups for urine volume, calcium or ammonium (NH4) excretion. There was a significant trend (p<0.001) for more met-s traits being associated with decreasing urine pH, increasing age, calculated dietary protein, urine uric acid, oxalate, citrate, titratable acid (TAP), net acid excretion (eNAE) and uric acid supersaturation. The ratio of ammonium to net acid excretion did not differ among the groups. After adjustment for protein intake, the fall in urine pH remained strong, while the upward trend in TAP excretion was attenuated and NH4 decreased. Calcium oxalate stones were most common, but there was a trend for more uric acid (p<0.001) and fewer calcium phosphate (p=0.09) and calcium oxalate stones (p=0.01) with more met-s traits. Conclusions: Stone forming patients with met-s have a defined pattern of metabolic and dietary risk factors that contribute to an increased risk of stone formation including higher acid excretion, largely the result of higher protein intake, and lower urine pH.

Dietary Factors in the Prevention and Treatment of Nonmelanoma Skin Cancer and Melanoma

2002 ◽  
Vol 28 (12) ◽  
pp. 1143-1152 ◽  
Author(s):  
TRACY L. BIALY ◽  
MARTI JILL ROTHE ◽  
JANE M. GRANT-KELS
Keyword(s):  
Skin Cancer ◽  
Nonmelanoma Skin Cancer ◽  
Dietary Factors ◽  
Prevention And Treatment

scholarly journals Predicting Type 2 Diabetes Incidence with Genome-wide Gene-gene and Gene-diet Interactions (OR31-08-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Crystal Sorgini ◽  
Jacob Christensen ◽  
Laurence Parnell ◽  
Katherine Tucker ◽  
Jose M Ordovas ◽  
...  
Keyword(s):  
Machine Learning ◽  
Type 2 Diabetes ◽  
Lifestyle Factors ◽  
Dietary Factors ◽  
Stochastic Gradient Boosting ◽  
Genome Wide ◽  
A Genome ◽  
Prevention And Treatment ◽  
Genome Wide Scan

Abstract Objectives To identify genetic and dietary factors, and their interactions that contribute to type 2 diabetes (T2D) and predict an individual's risk to design more precise prevention and treatment strategies. Methods A genome-wide scan for up to three-way interactions between 717,275 single nucleotide polymorphisms (SNPs), and 139 dietary and lifestyle factors was conducted on 1380 participants of the Boston Puerto Rican Health Study using the Generalized Multifactor Dimensionality Reduction (GMDR) method. Based on identified genetic and dietary factors, we then used machine learning (ML) to predict T2D risk, and the accuracy of prediction was assessed using area under the Receiver Operating Characteristic curve (ROC-AUC). Results A genome-wide scan for main effects and up to three-way interactions between SNPs and dietary factors using GMDR identified a set of 818 SNPs and 12 dietary factors that were selected for the prediction of T2D incidence. Comparing several ML algorithms, we found that stochastic gradient boosting provided the best prediction accuracy of T2D incidence with ROC-AUC of 0.93 in the training set, and overall accuracy of 85% based on test set validation. This approach identified that 52 SNPs in 37 genes, three food groups of high sugar content, and age were key predictors of the best-fit model. Conclusions This study illustrates a powerful methodology that can predict incidence of T2D based on gene-gene and gene-environment interactions in combination with machine learning. This genome-wide approach allows identification of those diet and lifestyle factors that interact with genotype and can inform personalized nutrition strategies for the prevention and treatment of T2D. Funding Sources This work was funded by the US Department of Agriculture, under agreement no. 8050-51000-098-00D, and NIH grants P01 AG023394, P50 HL105185, and R01 AG027087.

Association between dietary factors and calcium oxalate and magnesium ammonium phosphate urolithiasis in cats

2001 ◽  
Vol 219 (9) ◽  
pp. 1228-1237 ◽  
Author(s):  
Chalermpol Lekcharoensuk ◽  
Carl A. Osborne ◽  
Jody P. Lulich ◽  
Rosama Pusoonthornthum ◽  
Claudia A. Kirk ◽  
...  
Keyword(s):  
Calcium Oxalate ◽  
Ammonium Phosphate ◽  
Dietary Factors ◽  
Magnesium Ammonium Phosphate ◽  
Magnesium Ammonium

Associations between dry dietary factors and canine calcium oxalate uroliths

2002 ◽  
Vol 63 (3) ◽  
pp. 330-337 ◽  
Author(s):  
Chalermpol Lekcharoensuk ◽  
Carl A. Osborne ◽  
Jody P. Lulich ◽  
Rosama Pusoonthornthum ◽  
Claudia A. Kirk ◽  
...  
Keyword(s):  
Calcium Oxalate ◽  
Dietary Factors
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