Solitary nevus lipomatosus superficialis

Nevus lipomatosus superficialis is a rare form of hamartoma or connective tissue nevus that is characterized by the presence of ectopic adipose tissue within the dermis. They usually present as soft yellowish or skin colored papulonodules with a predilection for the buttocks, upper thigh, and lumbar back. We report a solitary form of nevus lipomatosus superficialis in a 63-year-old woman who presented with a skin colored pedunculated mass. Histopathology showed mature adipocytes in lobules extending to the papillary dermis.

Cicero Speaking with Solitudes

This chapter argues that the question of how one can “speak with oneself” (secum loqui) was central to Cicero’s personal, philosophical, and political projects throughout much of his career, and especially in his late works. Set against the background of scholarship on Cicero’s life and work, Petrarch’s interest in Cicero, and the wide arc of Cicero’s philosophical works, it studies Cicero’s dilations on the paradox of solitude—including Scipio’s adage, “Least alone when most alone”—in the years 46 to 43 BCE. It explores Cicero’s treatment of solitude in his letters (especially to Atticus) and in major works on either end of this period, works that rewrote social genres in solitary form: the Brutus and Orator, it shows, reimagined oratory in the deserted forum, while his Laelius de amicitia answered the question Aristotle had left hanging, and of great interest subsequently to Montaigne, whether persons can be friends to themselves.

Comprehensive Account on Prevalence and Characteristics of Hydatid Cysts in Livestock from Pakistan

Pakistan is at intersection of hyperendemic regions for hydatidosis. Current study aimed to determine the prevalence of hydatid cysts and cyst characteristics in different intermediate hosts (sheep, goats, cattle and buffaloes) across the 4 provinces of Pakistan. A total of 991 sheep, 1,478 goats, 1,602 cattle and 1,343 buffaloes were examined for presence of hydatid cysts during 2 years (January 2016-December 2018). Differences in frequency of hydatidosis were observed with highest overall prevalence in buffaloes (11.9%) and sheep (11.5%). Highest prevalence and burden of infection were observed in older age animals (23.8%, 9.78±0.49) and females (26.5%, 12.53±0.67). Data for seasonal prevalence alluded to year-round presence of disease with non-significant statistical difference. Organ predilection indicated liver as the most preferred site of cyst localization followed mainly by lungs. An over-dispersion pattern was observed in all infected animals as majority of cysts belonged <10 cysts per infected host category. Highest percentage of fertile cysts was observed in liver of sheep. Interestingly, solitary form of cysts had higher fertility rate than multiple form. Amid lack of data and wide gap of knowledge, this study would try to fill up the lacunae regarding this neglected tropical disease. Extensive rearing of livestock, unregulated official slaughter and home slaughtering have played role in adaptability of <i>E. granulosus</i> in Pakistan.

A GIANT PERINEAL NEVUS LIPOMATOSUS SUPERFICIALIS: CASE REPORT

Nevus lipomatosus superficialis is a rare hamartomatous malformation which is composed of ectopic adipocytes in the dermis. It was first reported in 1921 by Hoffmann and Zurhelle. Two clinical forms of nevus lipomatosus superficialis have been described: classical (multiple) and solitary. Classical form of nevus lipomatosus superficialis is usually found on pelvic girdle, trunk, buttocks and thighs as soft, skin colored papules or nodules. It is usually present at birth or it appears in the first two decades of life. The solitary form of lipomatosus superficialis appears as a solitary papule or nodule on the back, scalp and arms of the patients with late onset. The lesions are usually asymptomatic, however some patients may complain about pain and itching. Malignant transformation of nevus lipomatosis superficialis has not been reported yet. Therefore, surgical intervention is only necessary for the patients who have cosmetic concerns. Recurrence after surgical removal is very rare. Perineum is an uncommon localization for nevus lipomatosus superficialis. Hereby, we report a 55-year-old Caucasian female with a 6x5,5x4 cm mass in the perineal region. The patient had cosmetic concerns, therefore she wanted the lesion to be removed surgically. The lesion was surgically removed. The histopathological evaluation of the specimen revealed nevus lipomatosus superficialis. A solitary type of giant nevus lipomatosus superficialis in the perineal region of a patient over the age of 50 is a very rare condition. Even rarely seen, nevus lipomatosus superficialis should be kept in mind in the differential diagnosis of perineal masses.

Intracranial Castleman's disease of solitary form

✓ This 62-year-old woman presented with clumsiness in her right hand. Magnetic resonance imaging demonstrated a small lesion mimicking a meningioma, which had arisen from the tentorium and contained notable edema.Full recovery was achieved by total removal of the lesion, which was diagnosed as a lymphoid mass resembling giant lymph node hyperplasia on histological examination. The lack of notable findings on whole-body and laboratory studies was compatible with a rare case of intracranial Castleman's disease of solitary form. The authors document clinical, neuroradiological, and pathological features of this rare disease.