destructive osteoarthritis
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2021 ◽  
Vol 14 (6) ◽  
pp. e241203
Author(s):  
Harry David True ◽  
Rupert George Ricks ◽  
Joel Anthony Smith

We present a case of non-surgically managed bilateral osteonecrosis of the external auditory canal with a history of long-term medical therapy for osteoporosis. A 79-year-old woman with severe osteoporosis and destructive osteoarthritis received >10 years of once weekly bisphosphonate therapy before switching to denosumab. Four months later, the patient presented with bilateral loss of hearing and right-sided otalgia. Necrotising otitis externa, cholesteatoma and malignancy were considered but with histology, microbiological and CT assessment, bilateral osteonecrosis of the external auditory canal was diagnosed. Surgical debridement with canalplasty was avoided due to our patient’s comorbidities. Treatment continued for 5 months with regular aural toilet, Terra-Cortril ointment and bismuth-iodine-paraffin paste packing. At 1-year follow-up, bilateral external auditory canals were completely re-epithelialised with no pain or affected hearing. We report the first case of bilateral osteonecrosis of the external auditory canal associated with denosumab and bisphosphonates with successful conservative management.


Author(s):  
Felipe Matsunaga ◽  
Robert Russell DeVita ◽  
Peter Christopher Young

2019 ◽  
Vol 57 (4) ◽  
pp. e123-e124 ◽  
Author(s):  
Ryan Borst ◽  
Janet Anne Smereck ◽  
Jonathan E. Davis

2018 ◽  
Vol 4 (2) ◽  
pp. 184-186 ◽  
Author(s):  
Anurag Tiwari ◽  
Yugal Karkhur ◽  
James A. Keeney ◽  
Ajay Aggarwal

2018 ◽  
Vol 4 (2) ◽  
pp. 205-209 ◽  
Author(s):  
Shane R. Hess ◽  
Robert S. O'Connell ◽  
Christopher P. Bednarz ◽  
Andrew C. Waligora ◽  
Gregory J. Golladay ◽  
...  

2017 ◽  
Vol 8 ◽  
pp. S72-S75
Author(s):  
Elina Huerfano ◽  
Maria Bautista ◽  
Guillermo Bonilla ◽  
Mauricio Palau-Lazaro ◽  
Adolfo Llinás ◽  
...  

PM&R ◽  
2016 ◽  
Vol 8 (9) ◽  
pp. S212
Author(s):  
Rachel Welbel ◽  
Jaclyn H. Bonder

2016 ◽  
Vol 2 (1) ◽  
pp. 15-18 ◽  
Author(s):  
Gavin Hart ◽  
Thomas Fehring

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