Thermal Assessment of Power Cables and Impacts on Cable Current Rating: An Overview

The conceptual assessment of the rating conditions of power cables was addressed over one century ago, with theories based on the physical and heat transfer properties of the power cable installed in a given medium. During the years, the evolution of the computational methods and technologies has made more powerful means for executing the calculations available. More detailed configurations have been analysed, also moving from the steady-state to dynamic rating assessment. The research is in progress, with recent advances obtained on both advanced models, extensive calculations from 2D and 3D finite element methods, simplified approaches aimed at reducing the computational burden, and dedicated solutions for specific types of cables and applications. This paper provides a general overview that links the fundamental concepts of heat transfer for the calculation of cable rating to the advanced solutions that have emerged in the last years.

Two Histories of Bioinformatics: Data Science vs Life Science

This paper focuses on two attempts to reconstruct the history of bioinformatics as a scientific discipline. Paulien Hogeweg who coined the term “bioinformatics,” presents one of them, while Hallam Stevens, who is both a historian and sociologist of science, offers the other. Although both of them can speak authoritatively about bioinformatics inasmuch as Hogeweg was personally involved in creating the field while Stevens has amassed a substantial amount of microsociological, scientometric and other evidence, they tell two fundamentally different stories. According to Hogeweg, bioinformatics came about as a response to new epistemic demands on the life sciences that arose from several key discoveries in molecular biology in the middle of 20th century. For Stevens, the new discipline was the result of transplanting computational methods and technologies into biology. This difference stems from divergent interpretations of what bioinformatics is, and these in turn depend upon different ontological claims about the nature of living things. The link between the concepts of life and information is explained by Hogeweg through a systems approach. Stevens discounts that link and concentrates instead on the transposition of scientific practices from other disciplines and on the new ways of understanding the living which are generated by this transposition. The attempt to define bioinformatics as a scientific discipline ends for both of these theorists a tautology: the discipline is defined by something defined by this same discipline, that is, by a certain idea about information and/or data. The effect of this tautology is that a normative criterion for delimitation of disciplines (a set of requirements which are necessary and sufficient for considering a field of research as a scientific discipline) does not allow us to explain how each of them occurs individually. Instead, a descriptive criterion is proposed, which is to be understood as the study of the conditions which make possible the differentiations in scientific practices which have already taken place. A distinct understanding of information or data and the ontology associated with it should be the outcome of a study of this kind and not presupposed by it.

The EuroPhysiome, STEP and a roadmap for the virtual physiological human

Biomedical science and its allied disciplines are entering a new era in which computational methods and technologies are poised to play a prevalent role in supporting collaborative investigation of the human body. Within Europe, this has its focus in the virtual physiological human (VPH), which is an evolving entity that has emerged from the EuroPhysiome initiative and the strategy for the EuroPhysiome (STEP) consortium. The VPH is intended to be a solution to common infrastructure needs for physiome projects across the globe, providing a unifying architecture that facilitates integration and prediction, ultimately creating a framework capable of describing Homo sapiens in silico . The routine reliance of the biomedical industry, biomedical research and clinical practice on information technology (IT) highlights the importance of a tailor-made and robust IT infrastructure, but numerous challenges need to be addressed if the VPH is to become a mature technological reality. Appropriate investment will reap considerable rewards, since it is anticipated that the VPH will influence all sectors of society, with implications predominantly for improved healthcare, improved competitiveness in industry and greater understanding of (patho)physiological processes. This paper considers issues pertinent to the development of the VPH, highlighted by the work of the STEP consortium.