Feline cryptococcosis attended in the municipality of Sinop: Case report

Cryptococcosis is a non-contagious systemic mycosis caused by yeasts of the Cryptococcus genus, which can affect humans, domestic and wild animals. Transmission occurs through the inhalation of these airborne yeasts from contaminated environments. In domestic cats, it stands out for infection of the upper respiratory tract, of the cutaneous system, which can reach the central nervous system and still present itself in a disseminated form. Treatment is carried out through the use of antifungals such as fluconazole, itraconazole and amphotericin B for long periods. This article rehearses a case of cryptococcosis in a 10-year-old mixed breed feline with free access to the street. The animal has an ulcerative lesion in the nasal plane, nasal discharge, depression and anorexia. The diagnosis was identified through microbiological culture. Link the severity of the patient's condition to a conduct adopted for euthanasia. Early diagnosis is essential for the establishment of adequate treatment and a favorable prognosis since cryptococcosis, although rare, can be potentially fatal.

Acute Vogt-Koyanagi-Harada: a case report

Context: Vogt-Koyanagi-Harada disease is an inflammatory disorder, which presents with intraocular, auditory and central nervous system involvement. It has two distinct courses: acute onset and chronic recurrence, whose differential diagnoses are, respectively, diseases of the optic neuromyelitis spectrum, and chronic meningitis. The diagnostic criteria developed by the international disease committee in 2001 classify patients into: probable disease (ocular findings only), incomplete (ocular plus cutaneous system or neurological manifestations) and complete (when the three forms occur together). Methods: Report the case of a patient seen at the emergency room of Santa Casa de São Paulo, diagnosed with Vogt-Koyanagi-Harada disease. Case report: 43-year-old woman, reporting occipital headache, with irradiation to the retro-orbital region, progressed to sudden bilateral amaurosis, in addition to conjunctival hyperemia. Neurological physical examination presented bilateral visual acuity (Snellen)> 20/200, poorly delimited optical discs. Uveitis and scleritis were also found. Brain and orbit MRI showed: bilateral retinal detachment, with small subretinal collections; regular thickening and impregnation of the choroid; tenuous episcleral impregnation; alteration of the sign of the inner ears, more evident in the cochleae; tenuous linear leptomeningeal impregnation at the level of the cerebellobulbar cistern. Liquor: 21 cells (99% lymphocytes), 31 proteins and 47 glucose, negative culture for bacteria. We proceeded to infusion 1000mg of methylprednisolone for 3 days, with daily use, subsequently, of prednisone 60mg, with significant improvement of the condition. Conclusions: It is a rare disease, but it must be recognized by every neurologist, since it is treatable and can leave serious visual sequelae.