Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery

Kinetic Design for Establishing Long-Term Stationary Cytosol Concentrations During Drug Transport across P-gp Expressing Confluent Cell Monolayers to Facilitate Measuring Cytosol Concentration, Fitting Drug Molar Partition Coefficients into the Cytosolic Monolayer of the Plasma Membrane, and Kinetically Identifying Drug Uptake Transporters

Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery ◽

10.1007/978-1-0716-1250-7_2 ◽

2021 ◽

pp. 41-65

Author(s):

Joe Bentz

Keyword(s):

Plasma Membrane ◽

Partition Coefficients ◽

Drug Transport ◽

Drug Uptake ◽

Cell Monolayers ◽

Confluent Cell ◽

Uptake Transporters

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In Vitro Methodologies to Assess Potential for Transporter-Mediated Drug–Drug Interactions

Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery ◽

10.1007/978-1-0716-1250-7_3 ◽

2021 ◽

pp. 67-80

Author(s):

Jibin Li ◽

Qing Wang ◽

Ismael J. Hidalgo

Keyword(s):

Drug Interactions

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Measurement of Transcellular Transport Rates and Intracellular Drug Sequestration in the Presence of an Extracellular Concentration Gradient

Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery ◽

10.1007/978-1-0716-1250-7_1 ◽

2021 ◽

pp. 3-39

Author(s):

Kyoung Ah Min ◽

Gus R. Rosania

Keyword(s):

Concentration Gradient ◽

Transcellular Transport ◽

Extracellular Concentration ◽

Drug Sequestration

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Quantitative Phenotypic Analysis of Drug Sequestering Macrophage Subpopulations

Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery ◽

10.1007/978-1-0716-1250-7_7 ◽

2021 ◽

pp. 147-162

Author(s):

Mikhail D. Murashov

Keyword(s):

Phenotypic Analysis ◽

Macrophage Subpopulations

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Quantitative Determination of Intracellular Bond Cleavage

Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery ◽

10.1007/978-1-0716-1250-7_14 ◽

2021 ◽

pp. 305-330

Author(s):

Joshua A. Walker ◽

Michelle R. Sorkin ◽

Christopher A. Alabi

Keyword(s):

Quantitative Determination ◽

Bond Cleavage

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Intracellular Targeting of Cyclotides for Therapeutic Applications

Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery ◽

10.1007/978-1-0716-1250-7_11 ◽

2021 ◽

pp. 229-248

Author(s):

Nicole Lawrence ◽

David J. Craik

Keyword(s):

Therapeutic Applications ◽

Intracellular Targeting

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Contribution of Nontarget Cells to the Disposition, Antitumor Activity, and Antigen-Independent Toxicity of Antibody–Drug Conjugates

Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery ◽

10.1007/978-1-0716-1250-7_16 ◽

2021 ◽

pp. 357-382

Author(s):

David W. Meyer ◽

Fu Li ◽

Robert P. Lyon

Keyword(s):

Antitumor Activity ◽

Antibody Drug Conjugates ◽

Drug Conjugates ◽

Antibody Drug

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Cellular Trafficking of Monoclonal and Bispecific Antibodies

Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery ◽

10.1007/978-1-0716-1250-7_12 ◽

2021 ◽

pp. 249-274

Author(s):

John J. Rhoden ◽

Christopher M. Wiethoff

Keyword(s):

Bispecific Antibodies ◽

Cellular Trafficking

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Using an Integrated QSAR Model to Check Whether Small-Molecule Xenobiotics Will Accumulate in Biomembranes, with Particular Reference to Fluorescent Imaging Probes

Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery ◽

10.1007/978-1-0716-1250-7_8 ◽

2021 ◽

pp. 163-177

Author(s):

Richard W. Horobin ◽

Juan C. Stockert

Keyword(s):

Small Molecule ◽

Qsar Model ◽

Fluorescent Imaging ◽

Imaging Probes

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Development and Application of a Single Cell-Level PK-PD Model for ADCs

Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery ◽

10.1007/978-1-0716-1250-7_15 ◽

2021 ◽

pp. 331-355

Author(s):

Shufang Liu ◽

Dhaval K. Shah

Keyword(s):

Single Cell ◽

Single Cell Level ◽

Cell Level

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Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery
Latest Publications

TOTAL DOCUMENTS

H-INDEX

Published By Springer US

In Vitro Methodologies to Assess Potential for Transporter-Mediated Drug–Drug Interactions

Measurement of Transcellular Transport Rates and Intracellular Drug Sequestration in the Presence of an Extracellular Concentration Gradient

Quantitative Phenotypic Analysis of Drug Sequestering Macrophage Subpopulations

Quantitative Determination of Intracellular Bond Cleavage

Intracellular Targeting of Cyclotides for Therapeutic Applications

Contribution of Nontarget Cells to the Disposition, Antitumor Activity, and Antigen-Independent Toxicity of Antibody–Drug Conjugates

Cellular Trafficking of Monoclonal and Bispecific Antibodies

Using an Integrated QSAR Model to Check Whether Small-Molecule Xenobiotics Will Accumulate in Biomembranes, with Particular Reference to Fluorescent Imaging Probes

Development and Application of a Single Cell-Level PK-PD Model for ADCs

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Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and DeliveryLatest Publications

TOTAL DOCUMENTS

H-INDEX

Published By Springer US

In Vitro Methodologies to Assess Potential for Transporter-Mediated Drug–Drug Interactions

Measurement of Transcellular Transport Rates and Intracellular Drug Sequestration in the Presence of an Extracellular Concentration Gradient

Quantitative Phenotypic Analysis of Drug Sequestering Macrophage Subpopulations

Quantitative Determination of Intracellular Bond Cleavage

Intracellular Targeting of Cyclotides for Therapeutic Applications

Contribution of Nontarget Cells to the Disposition, Antitumor Activity, and Antigen-Independent Toxicity of Antibody–Drug Conjugates

Cellular Trafficking of Monoclonal and Bispecific Antibodies

Using an Integrated QSAR Model to Check Whether Small-Molecule Xenobiotics Will Accumulate in Biomembranes, with Particular Reference to Fluorescent Imaging Probes

Development and Application of a Single Cell-Level PK-PD Model for ADCs

Methods in Pharmacology and Toxicology - Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery
Latest Publications