Reactive Drug Metabolites - Methods and Principles in Medicinal Chemistry
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Published By Wiley-VCH Verlag Gmbh & Co. Kgaa

9783527655748, 9783527330850

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Bioactivation and Inactivation of Cytochrome P450 and Other Drug-Metabolizing Enzymes

Reactive Drug Metabolites - Methods and Principles in Medicinal Chemistry ◽

10.1002/9783527655748.ch3 ◽

2012 ◽

pp. 43-70

Keyword(s):

Cytochrome P450 ◽

Drug Metabolizing Enzymes ◽

Metabolizing Enzymes

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Bioactivation and Natural Products

Reactive Drug Metabolites - Methods and Principles in Medicinal Chemistry ◽

10.1002/9783527655748.ch9 ◽

2012 ◽

pp. 203-224 ◽

Keyword(s):

Natural Products

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Experimental Approaches to Reactive Metabolite Detection

Reactive Drug Metabolites - Methods and Principles in Medicinal Chemistry ◽

10.1002/9783527655748.ch10 ◽

2012 ◽

pp. 225-240

Keyword(s):

Reactive Metabolite ◽

Experimental Approaches ◽

Metabolite Detection

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Index

Reactive Drug Metabolites - Methods and Principles in Medicinal Chemistry ◽

10.1002/9783527655748.index ◽

2012 ◽

pp. 377-385

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Intrinsically Electrophilic Compounds as a Liability in Drug Discovery

Reactive Drug Metabolites - Methods and Principles in Medicinal Chemistry ◽

10.1002/9783527655748.ch6 ◽

2012 ◽

pp. 131-143

Keyword(s):

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Mitigating Toxicity Risks with Affinity Labeling Drug Candidates

Reactive Drug Metabolites - Methods and Principles in Medicinal Chemistry ◽

10.1002/9783527655748.ch13 ◽

2012 ◽

pp. 313-334 ◽

Keyword(s):

Affinity Labeling ◽

Drug Candidates

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Dealing with Reactive Metabolite-Positive Compounds in Drug Discovery

Reactive Drug Metabolites - Methods and Principles in Medicinal Chemistry ◽

10.1002/9783527655748.ch14 ◽

2012 ◽

pp. 335-355

Keyword(s):

Drug Discovery ◽

Reactive Metabolite

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Role of Reactive Metabolites in Drug-Induced Toxicity - The Tale of Acetaminophen, Halothane, Hydralazine, and Tienilic Acid

Reactive Drug Metabolites - Methods and Principles in Medicinal Chemistry ◽

10.1002/9783527655748.ch4 ◽

2012 ◽

pp. 71-92

Keyword(s):

Reactive Metabolites ◽

Drug Induced ◽

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Structural Alert and Reactive Metabolite Analysis for the Top 200 Drugs in the US Market by Prescription

Reactive Drug Metabolites - Methods and Principles in Medicinal Chemistry ◽

10.1002/9783527655748.ch12 ◽

2012 ◽

pp. 269-312

Keyword(s):

Reactive Metabolite ◽

Metabolite Analysis ◽

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Pathways of Reactive Metabolite Formation with Toxicophores/-Structural Alerts

Reactive Drug Metabolites - Methods and Principles in Medicinal Chemistry ◽

10.1002/9783527655748.ch5 ◽

2012 ◽

pp. 93-129 ◽

Keyword(s):

Reactive Metabolite ◽

Metabolite Formation ◽

Structural Alerts

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