Optimization in Drug Discovery
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Published By Humana Press

9781588293329, 9781592598007
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Use of Caco-2 Cell Monolayers to Study Drug Absorption and Metabolism

2004 ◽  
pp. 19-35 ◽  
Author(s):  
Ming Hu ◽  
Jie Ling ◽  
Huimin Lin ◽  
Jun Chen
Keyword(s):  
Drug Absorption ◽  
Study Drug ◽  
Cell Monolayers

In Vitro Permeation Study With Bovine Brain Microvessel Endothelial Cells

2004 ◽  
pp. 77-87 ◽  
Author(s):  
Seong-Hee Park ◽  
Sung-Hack Lee ◽  
Yaming Su ◽  
Patrick J. Sinko
Keyword(s):  
Endothelial Cells ◽  
Bovine Brain ◽  
Permeation Study ◽  
In Vitro Permeation ◽  
Microvessel Endothelial Cells ◽  
Brain Microvessel

Identification of CYP Mechanism-Based Inhibitors

2004 ◽  
pp. 245-262 ◽  
Author(s):  
Amin A. Nomeir ◽  
Jairam R. Palamanda ◽  
Leonard Favreau

In Vitro Drug Metabolism

2004 ◽  
pp. 369-383 ◽  
Author(s):  
Wei Tang ◽  
Randy R. Miller
Keyword(s):  
Drug Metabolism

Detection of DNA Adducts by 32P-Postlabeling Analysis

2004 ◽  
pp. 263-278 ◽  
Author(s):  
Naomi Suzuki ◽  
Padmaja M. Prabhu ◽  
Shinya Shibutani
Keyword(s):  
Dna Adducts

In Situ Single-Pass Perfused Rat Intestinal Model for Absorption and Metabolism

2004 ◽  
pp. 65-76 ◽  
Author(s):  
Eun Ju Jeong ◽  
Yan Liu ◽  
Huimin Lin ◽  
Ming Hu
Keyword(s):  
Single Pass

In Vitro CYP Induction in Human Hepatocytes

2004 ◽  
pp. 203-214
Author(s):  
Daniel R. Mudra ◽  
Andrew Parkinson
Keyword(s):  
Human Hepatocytes ◽  
Cyp Induction

Absorption Screening Using the PAMPA Approach

2004 ◽  
pp. 37-64 ◽  
Author(s):  
Jeffrey A. Ruell ◽  
Alex Avdeef
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