Target Identification and Validation in Drug Discovery - Methods in Molecular Biology
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Published By Springer New York

9781493991440, 9781493991457

Latest Documents Most Cited Documents Contributed Authors Related Sources Related Keywords

Integration of RNAi and Small Molecule Screens to Identify Targets for Drug Development

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-4939-9145-7_3 ◽

2019 ◽

pp. 33-42

Author(s):

Konstantinos Drosopoulos ◽

Spiros Linardopoulos

Keyword(s):

Drug Development ◽

Small Molecule

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Chromogenic Tissue-Based Methods for Detection of Gene Amplifications (or Rearrangements) Combined with Protein Overexpression in Clinical Samples

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-4939-9145-7_19 ◽

2019 ◽

pp. 301-314 ◽

Cited By ~ 2

Author(s):

Hiroaki Nitta ◽

Brian Kelly

Keyword(s):

Clinical Samples ◽

Protein Overexpression

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Expression of Human VH Single Domains as Fc Fusions in Mammalian Cells

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-4939-9145-7_8 ◽

2019 ◽

pp. 121-136

Author(s):

Mahmoud Abdelatti ◽

Peter Schofield ◽

Daniel Christ

Keyword(s):

Mammalian Cells

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In Silico Target Druggability Assessment: From Structural to Systemic Approaches

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-4939-9145-7_5 ◽

2019 ◽

pp. 63-88 ◽

Cited By ~ 2

Author(s):

Jean-Yves Trosset ◽

Christian Cavé

Keyword(s):

In Silico

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Creation of PDX-Bearing Humanized Mice to Study Immuno-oncology

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-4939-9145-7_15 ◽

2019 ◽

pp. 241-252 ◽

Cited By ~ 12

Author(s):

Li-Chin Yao ◽

Ken-Edwin Aryee ◽

Mingshan Cheng ◽

Pali Kaur ◽

James G. Keck ◽

...

Keyword(s):

Humanized Mice

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Unbiased Forward Genetic Screening with Chemical Mutagenesis to Uncover Drug–Target Interactions

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-4939-9145-7_2 ◽

2019 ◽

pp. 23-31

Author(s):

Moritz Horn ◽

Franziska Metge ◽

Martin S. Denzel

Keyword(s):

Genetic Screening ◽

Drug Target ◽

Chemical Mutagenesis

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Combined MicroRNA In Situ Hybridization and Immunohistochemical Detection of Protein Markers

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-4939-9145-7_17 ◽

2019 ◽

pp. 271-286

Author(s):

Boye Schnack Nielsen ◽

Kim Holmstrøm

Keyword(s):

In Situ Hybridization ◽

Immunohistochemical Detection ◽

Protein Markers

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Establishment and Analysis of a 3D Co-Culture Spheroid Model of Pancreatic Adenocarcinoma for Application in Drug Discovery

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-4939-9145-7_11 ◽

2019 ◽

pp. 163-179 ◽

Cited By ~ 2

Author(s):

Julia C. Meier-Hubberten ◽

Michael P. Sanderson

Keyword(s):

Drug Discovery ◽

Pancreatic Adenocarcinoma

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Tangential Flow Filtration with or Without Subsequent Bind-Elute Size Exclusion Chromatography for Purification of Extracellular Vesicles

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-4939-9145-7_18 ◽

2019 ◽

pp. 287-299 ◽

Cited By ~ 3

Author(s):

Joel Z. Nordin ◽

R. Beklem Bostancioglu ◽

Giulia Corso ◽

Samir EL Andaloussi

Keyword(s):

Size Exclusion Chromatography ◽

Extracellular Vesicles ◽

Size Exclusion ◽

Tangential Flow Filtration ◽

Tangential Flow ◽

Exclusion Chromatography ◽

Flow Filtration

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Use of CRISPR/Cas9 for the Modification of the Mouse Genome

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology ◽

10.1007/978-1-4939-9145-7_13 ◽

2019 ◽

pp. 213-230 ◽

Cited By ~ 2

Author(s):

Alexander Klimke ◽

Steffen Güttler ◽

Petric Kuballa ◽

Simone Janzen ◽

Sonja Ortmann ◽

...

Keyword(s):

Mouse Genome

Download Full-text

Target Identification and Validation in Drug Discovery - Methods in Molecular BiologyLatest Publications

TOTAL DOCUMENTS

H-INDEX

Published By Springer New York

Integration of RNAi and Small Molecule Screens to Identify Targets for Drug Development

Chromogenic Tissue-Based Methods for Detection of Gene Amplifications (or Rearrangements) Combined with Protein Overexpression in Clinical Samples

Expression of Human VH Single Domains as Fc Fusions in Mammalian Cells

In Silico Target Druggability Assessment: From Structural to Systemic Approaches

Creation of PDX-Bearing Humanized Mice to Study Immuno-oncology

Unbiased Forward Genetic Screening with Chemical Mutagenesis to Uncover Drug–Target Interactions

Combined MicroRNA In Situ Hybridization and Immunohistochemical Detection of Protein Markers

Establishment and Analysis of a 3D Co-Culture Spheroid Model of Pancreatic Adenocarcinoma for Application in Drug Discovery

Tangential Flow Filtration with or Without Subsequent Bind-Elute Size Exclusion Chromatography for Purification of Extracellular Vesicles

Use of CRISPR/Cas9 for the Modification of the Mouse Genome

Target Identification and Validation in Drug Discovery - Methods in Molecular Biology
Latest Publications