Methods in Pharmacology and Toxicology - Drug-Induced Liver Toxicity
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Published By Springer New York

9781493976768, 9781493976775

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Use of Liver-Derived Cell Lines for the Study of Drug-Induced Liver Injury

Methods in Pharmacology and Toxicology - Drug-Induced Liver Toxicity ◽

10.1007/978-1-4939-7677-5_8 ◽

2018 ◽

pp. 151-177 ◽

Author(s):

Zhen Ren ◽

Si Chen ◽

Baitang Ning ◽

Lei Guo

Keyword(s):

Liver Injury ◽

Drug Induced ◽

Drug Induced Liver Injury

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Circulating MicroRNAs as Novel Biomarkers of Drug-Induced Liver Injury in Humans

Methods in Pharmacology and Toxicology - Drug-Induced Liver Toxicity ◽

10.1007/978-1-4939-7677-5_28 ◽

2018 ◽

pp. 597-610 ◽

Author(s):

Julian Krauskopf ◽

Jos C. Kleinjans ◽

Theo M. de Kok

Keyword(s):

Liver Injury ◽

Drug Induced ◽

Circulating Micrornas ◽

Drug Induced Liver Injury ◽

Novel Biomarkers

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Drug-Induced Liver Injury (DILI) Classification and Its Application on Human DILI Risk Prediction

Methods in Pharmacology and Toxicology - Drug-Induced Liver Toxicity ◽

10.1007/978-1-4939-7677-5_3 ◽

2018 ◽

pp. 45-59 ◽

Author(s):

Shraddha Thakkar ◽

Minjun Chen ◽

Huixiao Hong ◽

Zhichao Liu ◽

Hong Fang ◽

...

Keyword(s):

Liver Injury ◽

Risk Prediction ◽

Drug Induced ◽

Drug Induced Liver Injury

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Quantitative Structure–Activity Relationship Models for Predicting Risk of Drug-Induced Liver Injury in Humans

Methods in Pharmacology and Toxicology - Drug-Induced Liver Toxicity ◽

10.1007/978-1-4939-7677-5_5 ◽

2018 ◽

pp. 77-100 ◽

Author(s):

Huixiao Hong ◽

Jieqiang Zhu ◽

Minjun Chen ◽

Ping Gong ◽

Chaoyang Zhang ◽

...

Keyword(s):

Liver Injury ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Drug Induced ◽

Drug Induced Liver Injury ◽

Structure Activity

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Interpretation, Integration, and Implementation of In Vitro Assay Data: The Predictive Toxicity Challenge

Methods in Pharmacology and Toxicology - Drug-Induced Liver Toxicity ◽

10.1007/978-1-4939-7677-5_17 ◽

2018 ◽

pp. 345-364 ◽

Author(s):

Deborah S. Light ◽

Michael D. Aleo ◽

J. Gerry Kenna

Keyword(s):

In Vitro Assay ◽

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Causality Assessment Methods in Drug-Induced Liver Injury

Methods in Pharmacology and Toxicology - Drug-Induced Liver Toxicity ◽

10.1007/978-1-4939-7677-5_27 ◽

2018 ◽

pp. 555-594 ◽

Author(s):

Rolf Teschke ◽

Gaby Danan

Keyword(s):

Liver Injury ◽

Causality Assessment ◽

Assessment Methods ◽

Drug Induced ◽

Drug Induced Liver Injury

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Physicochemical Properties and Structural Alerts

Methods in Pharmacology and Toxicology - Drug-Induced Liver Toxicity ◽

10.1007/978-1-4939-7677-5_4 ◽

2018 ◽

pp. 61-76 ◽

Author(s):

Lilia Fisk ◽

Nigel Greene ◽

Russ Naven

Keyword(s):

Physicochemical Properties ◽

Structural Alerts

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Variability in Baseline Liver Test Values in Clinical Trials: Challenges in Enhancing Drug-Induced Liver Injury Assessment in Subjects with Liver Disease

Methods in Pharmacology and Toxicology - Drug-Induced Liver Toxicity ◽

10.1007/978-1-4939-7677-5_21 ◽

2018 ◽

pp. 431-457

Author(s):

Bereket Tesfaldet ◽

Gyorgy Csako ◽

Tejas Patel ◽

Md Shamsuzzaman ◽

Eileen Navarro Almario

Keyword(s):

Clinical Trials ◽

Liver Disease ◽

Liver Injury ◽

Drug Induced ◽

Drug Induced Liver Injury ◽

Injury Assessment

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Reactive Metabolite Assessment in Drug Discovery and Development in Support of Safe Drug Design

Methods in Pharmacology and Toxicology - Drug-Induced Liver Toxicity ◽

10.1007/978-1-4939-7677-5_13 ◽

2018 ◽

pp. 263-281

Author(s):

Axel Pähler

Keyword(s):

Drug Discovery ◽

Drug Design ◽

Reactive Metabolite ◽

Drug Discovery And Development

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Noninvasive Preclinical and Clinical Imaging of Liver Transporter Function Relevant to Drug-Induced Liver Injury

Methods in Pharmacology and Toxicology - Drug-Induced Liver Toxicity ◽

10.1007/978-1-4939-7677-5_30 ◽

2018 ◽

pp. 627-651 ◽

Author(s):

J. Gerry Kenna ◽

John C. Waterton ◽

Andreas Baudy ◽

Aleksandra Galetin ◽

Catherine D. G. Hines ◽

...

Keyword(s):

Liver Injury ◽

Drug Induced ◽

Clinical Imaging ◽

Drug Induced Liver Injury

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