scholarly journals Brain Monoamine Oxidase A Binding in Major Depressive Disorder

2009 ◽  
Vol 66 (12) ◽  
pp. 1304 ◽  
Author(s):  
Jeffrey H. Meyer ◽  
Alan A. Wilson ◽  
Sandra Sagrati ◽  
Laura Miler ◽  
Pablo Rusjan ◽  
...  
2011 ◽  
Vol 36 (10) ◽  
pp. 2139-2148 ◽  
Author(s):  
Shakevia Johnson ◽  
Craig A Stockmeier ◽  
Jeffrey H Meyer ◽  
Mark C Austin ◽  
Paul R Albert ◽  
...  

CNS Spectrums ◽  
2013 ◽  
Vol 18 (s1) ◽  
pp. 22-33 ◽  
Author(s):  
Thomas L. Schwartz

The goal of this brief review is to explain the role of monoamine oxidase enzymes in the neurobiology, etiology, and presentation of psychiatric illnesses, primarily major depressive disorder. This article will initially focus on the basic science and function of the monoamine oxidase system and some proposed neuropsychiatric symptoms that may arise if this enzyme system is altered by genetic predisposition. These findings and theories will next be translationally discussed in regard to clinical application pertaining to enzyme inhibition and the treatment of major depressive and other psychiatric disorders.


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