Effect of Prophylactic Subcutaneous Scopolamine Butylbromide on Death Rattle in Patients at the End of Life

JAMA ◽  
2021 ◽  
Vol 326 (13) ◽  
pp. 1268
Author(s):  
Harriëtte J. van Esch ◽  
Lia van Zuylen ◽  
Eric C. T. Geijteman ◽  
Esther Oomen-de Hoop ◽  
Bregje A. A. Huisman ◽  
...  

Introduction 586 Noisy breathing: ‘death rattle’ 587 Terminal agitation 588 Common symptoms at the end of life include: • Noisy breathing (‘death rattle’). • Pain. • Restlessness. • Agitation. • Confusion. • Breathlessness. • Weakness. • Nausea and vomiting. When managing symptoms at the end of life, it is not usually appropriate to undertake investigations unless they will influence the choice of treatment offered, e.g. to exclude reversible causes....


2012 ◽  
Vol 2 (Suppl 1) ◽  
pp. A64.3-A65
Author(s):  
Thiru Thirukumaran ◽  
Sivakumar Subramaniam ◽  
Declan Cawley ◽  
Simon Fisher
Keyword(s):  

2021 ◽  
Author(s):  
Alireza Irajpour ◽  
maryam hashemi ◽  
Fariba Taleghani

Abstract PurposeThis study seeks to adapt a guideline for end-of-life care in patients with cancer to be used by healthcare teams.MethodsThis methodological study was conducted by modifying the ADAPTE process and adding to it a qualitative study and consensus ratings by a multidisciplinary panel of experts. A qualitative study was thus performed to identify the end-of-life needs of patients with cancer. Then, the source guidelines and the results of the qualitative study were used to draft the initial version of the guideline, with 85 adaptation recommendations. A multidisciplinary panel of healthcare experts performed the external review of the recommendations based on the four criteria of relatedness, comprehensibility, usefulness, and feasibility and scored them on a scale of 1-9. The mean score of each recommendation was calculated, and the recommendations were classified into three categories: Appropriate (mean score of 7-9), uncertain (mean score of 4-6.99), and inappropriate (mean score of 1-3.99).ResultsAll the recommendations were approved, as they all had a mean score of 7 or higher, and were then categorized into 11 dimensions: Communication management; participatory and evidence-based decision-making management; pain management; dyspnea management; nausea and vomiting management; anorexia and cachexia management; constipation management; death rattle management; management of delirium, anxiety, and restlessness; hydration management; and pharmacological considerations.ConclusionThe adaptation of the guideline for end-of-life care in patients with cancer in Iran was performed by modifying the ADAPTE process with the participation of multidisciplinary stakeholders and based on the local needs.


2013 ◽  
Vol 22 (2) ◽  
pp. 81-85 ◽  
Author(s):  
Shelagh Twomey ◽  
Maura Dowling
Keyword(s):  

2019 ◽  
pp. bmjspcare-2018-001729 ◽  
Author(s):  
Martine E Lokker ◽  
Agnes van der Heide ◽  
Wendy H Oldenmenger ◽  
Carin C D van der Rijt ◽  
Lia van Zuylen

ObjectivesAt the end of life oral fluid intake is often reduced. Consensus about the most appropriate management for terminally ill patients with limited oral fluid intake is lacking. The objective of this study is to investigate to what extent the amount of fluid intake, preceding and during the dying phase, is related to the occurrence of death rattle and terminal restlessness.MethodsA multicentre prospective observational study was performed. Data on the occurrence of death rattle and terminal restlessness, fluid intake and opioid use of patients expected to die within a few days or hours were collected.Results371 patients were included. Death rattle was reported at least once in 40% (n=149) of patients during the dying phase. Death rattle occurrence was not associated with the amount of fluid intake during the days before dying. Terminal restlessness was reported in 26% of patients (n=96). Terminal restlessness was not associated with a lower amount of fluid intake during the days before dying. Terminal restlessness during the last 24 hours of life was associated with a higher amount of fluid (ie, >250 mL/day) during 48–25 hours before death.ConclusionsCaution with fluid intake to prevent development of death rattle does not seem to be necessary. Our study suggests that a higher amount of fluid intake during 48–25 hours before death may be associated with the occurrence of terminal restlessness during the last 24 hours of life. These results suggest that actively providing dying patients with artificial fluid may not be beneficial.


2020 ◽  
Vol 29 (1) ◽  
pp. 179-185 ◽  
Author(s):  
Daniel Dayan ◽  
Sasson Menahem ◽  
Pesach Shvartzman
Keyword(s):  

JAMA ◽  
2021 ◽  
Vol 326 (13) ◽  
pp. 1263
Author(s):  
Jared R. Lowe ◽  
Laura C. Hanson

Author(s):  
Susi Lund

At the end of life, it is important to review all medications, and those required may be continued via a syringe driver if the person is unable to take them orally. The anticipation of needs and forward planning are important, having medications and resources available, ensuring all service providers are aware of the patient 24 hours a day and families have relevant contact numbers. Effective communication with the patient and family is essential, to manage expectations and ensure they understand what is being done and why. Care should always be planned in accordance with local and national guidelines in best practice in palliative and end-of-life care. Anticipatory prescribing of as-required medications for symptoms can help avoid distress. Respiratory secretions (death rattle) can cause noisy, rattling breathing that occurs when the dying person is unconscious and close to death and is unable to cough or clear secretions. This can be distressing to family members, and they will need support and information about the condition. Nursing care involves repositioning to aid drainage of secretions, frequent mouth care, and review of fluid input, and drugs may be used to reduce secretions. Terminal agitation is a state of agitation and distress at the end of life. This is a distressing experience, and it is most important to communicate effectively with the patient and family, maintaining dignity and privacy and providing a comforting professional presence. Sedation should be used with care and discretion, taking the wishes of the patient and family into account.


2019 ◽  
Vol 28 (3) ◽  
pp. 1356-1362
Author(s):  
Laurence Tan Lean Chin ◽  
Yu Jun Lim ◽  
Wan Ling Choo

Purpose Palliative care is a philosophy of care that encompasses holistic, patient-centric care involving patients and their family members and loved ones. Palliative care patients often have complex needs. A common challenge in managing patients near their end of life is the complexity of navigating clinical decisions and finding achievable and realistic goals of care that are in line with the values and wishes of patients. This often results in differing opinions and conflicts within the multidisciplinary team. Conclusion This article describes a tool derived from the biopsychosocial model and the 4-quadrant ethical model. The authors describe the use of this tool in managing a patient who wishes to have fried chicken despite aspiration risk and how this tool was used to encourage discussions and reduce conflict and distress within the multidisciplinary team.


2005 ◽  
Vol 14 (3) ◽  
pp. 15-19 ◽  
Author(s):  
Melanie Fried-Oken ◽  
Lisa Bardach

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