Diagnostic Strategies for Suspected Pulmonary Embolism

JAMA ◽  
2021 ◽  
Vol 326 (21) ◽  
pp. 2135
Author(s):  
Marcel Levi ◽  
Nick van Es
Keyword(s):  
Pulmonary Embolism ◽  
Suspected Pulmonary Embolism ◽  
Diagnostic Strategies

Diagnostic Strategies for Suspected Pulmonary Embolism Among Outpatients

2001 ◽  
Vol 01 (02) ◽  
pp. 189-194 ◽  
Author(s):  
Henri Bounameaux ◽  
Arnaud Perrier ◽  
Philip S. Wells
Keyword(s):  
Pulmonary Embolism ◽  
Suspected Pulmonary Embolism ◽  
Diagnostic Strategies

Equipment availability and diagnostic strategies for suspected pulmonary embolism in Austria

2001 ◽  
Vol 11 (11) ◽  
pp. 2287-2294 ◽  
Author(s):  
N. Schibany ◽  
D. Fleischmann ◽  
C. Thallinger ◽  
A. Schibany ◽  
J. Hahne ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Suspected Pulmonary Embolism ◽  
Diagnostic Strategies ◽  
Equipment Availability

The cost-effectiveness of diagnostic strategies in patients with suspected pulmonary embolism

1996 ◽  
Vol 5 (4) ◽  
pp. 307-318 ◽  
Author(s):  
Bowine C. Michel ◽  
Rob J. Seerden ◽  
Frans F. H. Rutten ◽  
Edwin J. R. van Beek ◽  
Harry R. Büller
Keyword(s):  
Pulmonary Embolism ◽  
Cost Effectiveness ◽  
Suspected Pulmonary Embolism ◽  
Diagnostic Strategies ◽  
The Cost

INFLUENCE OF AGE ON THE COST EFFECTIVENESS OF DIAGNOSTIC STRATEGIES FOR SUSPECTED PULMONARY EMBOLISM

2007 ◽  
Vol 5 ◽  
pp. P-W-502-P-W-502
Author(s):  
M. Righini ◽  
M. Nendaz ◽  
G. Le Gal ◽  
H. Bounameaux ◽  
A. Perrier
Keyword(s):  
Pulmonary Embolism ◽  
Cost Effectiveness ◽  
Suspected Pulmonary Embolism ◽  
Diagnostic Strategies ◽  
The Cost

Acute Pulmonary Embolism: Impact of Selection Bias in Prospective Diagnostic Studies

2001 ◽  
Vol 85 (04) ◽  
pp. 604-608 ◽  
Author(s):  
M.H. Prins ◽  
H.R. Büller ◽  
J.D. Banga ◽  
I.J.C. Hartmann ◽  
Keyword(s):  
Pulmonary Embolism ◽  
Selection Bias ◽  
Acute Pulmonary Embolism ◽  
Patient Characteristics ◽  
Pulmonary Angiography ◽  
Suspected Pulmonary Embolism ◽  
Diagnostic Strategies ◽  
A Prospective Study ◽  
Diagnostic Technologies ◽  
Patient Selection Bias

SummaryWe evaluated selection bias in a prospective study of 1162 consecutive patients with suspected pulmonary embolism. Of these, 983 were eligible, and 627 could actually be included. During two months extensive data were collected on all non-included patients. Finally, our patient characteristics were compared with those of the PIOPED study (1990) and the study of Hull et al. (1994). Compared with included patients, the non-included patients had more often non-diagnostic V/Q scans (50% vs. 36%, p <0.01) and were more often already hospitalized (31% vs. 22%, P = 0.04). The subgroup of patients not included due to refusal or inability to give informed consent (IC) was older (mean age 61 vs. 53 years, P <0.01), more often suffered from malignancies (26% vs. 11%, P <0.01) and frequently had non-diagnostic V/Q scans (57%) as compared to included patients. In our study, 54% of all patients screened was eventually included versus 27% in the PIOPED study. In the PIOPED study patients who had contra-indications for pulmonary angiography were excluded, while in the study of Hull et al. those with inadequate cardiorespiratory reserve were excluded. In studies on new diagnostic technologies, patient selection bias does occur. The potential for such a selection bias should be taken into account when diagnostic strategies are devised to improve their generalizability and acceptability.

scholarly journals Influence of age on the cost-effectiveness of diagnostic strategies for suspected pulmonary embolism

2007 ◽  
Vol 5 (9) ◽  
pp. 1869-1877 ◽  
Author(s):  
M. RIGHINI ◽  
M. NENDAZ ◽  
G. LE GAL ◽  
H. BOUNAMEAUX ◽  
A. PERRIER
Keyword(s):  
Pulmonary Embolism ◽  
Cost Effectiveness ◽  
Suspected Pulmonary Embolism ◽  
Diagnostic Strategies ◽  
The Cost

scholarly journals Ruling out Pulmonary Embolism in Patients with (Suspected) COVID-19—A Prospective Cohort Study

TH Open ◽  
2021 ◽  
Vol 05 (03) ◽  
pp. e387-e399
Author(s):  
Milou A.M. Stals ◽  
Fleur H.J. Kaptein ◽  
Remy H.H. Bemelmans ◽  
Thomas van Bemmel ◽  
Inge C. Boukema ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Pulmonary Embolism ◽  
Failure Rate ◽  
Outcome Study ◽  
Suspected Pulmonary Embolism ◽  
Thrombotic Risk ◽  
Diagnostic Strategies ◽  
Opt Out ◽  
Wells Rule

Abstract Background Diagnostic strategies for suspected pulmonary embolism (PE) have not been prospectively evaluated in COVID-19 patients. Methods Prospective, multicenter, outcome study in 707 patients with both (suspected) COVID-19 and suspected PE in 14 hospitals. Patients on chronic anticoagulant therapy were excluded. Informed consent was obtained by opt-out approach. Patients were managed by validated diagnostic strategies for suspected PE. We evaluated the safety (3-month failure rate) and efficiency (number of computed tomography pulmonary angiographies [CTPAs] avoided) of the applied strategies. Results Overall PE prevalence was 28%. YEARS was applied in 36%, Wells rule in 4.2%, and “CTPA only” in 52%; 7.4% was not tested because of hemodynamic or respiratory instability. Within YEARS, PE was considered excluded without CTPA in 29%, of which one patient developed nonfatal PE during follow-up (failure rate 1.4%, 95% CI 0.04–7.8). One-hundred seventeen patients (46%) managed according to YEARS had a negative CTPA, of whom 10 were diagnosed with nonfatal venous thromboembolism (VTE) during follow-up (failure rate 8.8%, 95% CI 4.3–16). In patients managed by CTPA only, 66% had an initial negative CTPA, of whom eight patients were diagnosed with a nonfatal VTE during follow-up (failure rate 3.6%, 95% CI 1.6–7.0). Conclusion Our results underline the applicability of YEARS in (suspected) COVID-19 patients with suspected PE. CTPA could be avoided in 29% of patients managed by YEARS, with a low failure rate. The failure rate after a negative CTPA, used as a sole test or within YEARS, was non-negligible and reflects the high thrombotic risk in these patients, warranting ongoing vigilance.

Diagnostic strategies for suspected pulmonary embolism

Imaging ◽  
2004 ◽  
pp. 89-105 ◽  
Author(s):  
M. Pistolesi ◽  
F. Lavorini ◽  
G. Allescia ◽  
M. Miniati
Keyword(s):  
Pulmonary Embolism ◽  
Suspected Pulmonary Embolism ◽  
Diagnostic Strategies
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