Olfactory system in mammals: structural and functional anatomy

Flavour ◽  
2016 ◽  
pp. 1-33 ◽  
Author(s):  
Anne-Marie Le Bon ◽  
Frédérique Datiche ◽  
Jean Gascuel ◽  
Xavier Grosmaitre
Author(s):  
James E. Crandall ◽  
Linda C. Hassinger ◽  
Gerald A. Schwarting

Cell surface glycoconjugates are considered to play important roles in cell-cell interactions in the developing central nervous system. We have previously described a group of monoclonal antibodies that recognize defined carbohydrate epitopes and reveal unique temporal and spatial patterns of immunoreactivity in the developing main and accessory olfactory systems in rats. Antibody CC2 reacts with complex α-galactosyl and α-fucosyl glycoproteins and glycolipids. Antibody CC1 reacts with terminal N-acetyl galactosamine residues of globoside-like glycolipids. Antibody 1B2 reacts with β-galactosyl glycolipids and glycoproteins. Our light microscopic data suggest that these antigens may be located on the surfaces of axons of the vomeronasal and olfactory nerves as well as on some of their target neurons in the main and accessory olfactory bulbs.


2019 ◽  
Vol 4 (4) ◽  
pp. 648-655
Author(s):  
William G. Pearson ◽  
Jacline V. Griffeth ◽  
Alexis M. Ennis

Purpose Rehabilitation of pharyngeal swallowing dysfunction requires a thorough understanding of the functional anatomy underlying the performance goals of pharyngeal swallowing. These goals include the safe and efficient transfer of a bolus through the hypopharynx into the esophagus. Penetration or aspiration of a bolus threatens swallowing safety. Bolus residue indicates swallowing inefficiency. Several primary mechanics, or elements of the swallowing mechanism, underlie these performance goals, with some elements contributing to both goals. These primary mechanics include velopharyngeal port closure, hyoid movement, laryngeal elevation, pharyngeal shortening, tongue base retraction, and pharyngeal constriction. Each element of the swallowing mechanism is under neuromuscular control and is therefore, in principle, a potential target for rehabilitation. Secondary mechanics of pharyngeal swallowing, those movements dependent on primary mechanics, include opening the upper esophageal sphincter and epiglottic inversion. Conclusion Understanding the functional anatomy of pharyngeal swallowing underlying swallowing performance goals will facilitate anatomically informed critical thinking in the rehabilitation of pharyngeal swallowing dysfunction.


2003 ◽  
Vol 14 (3) ◽  
pp. 181-190 ◽  
Author(s):  
Walter Sturm

Abstract: Behavioral and PET/fMRI-data are presented to delineate the functional networks subserving alertness, sustained attention, and vigilance as different aspects of attention intensity. The data suggest that a mostly right-hemisphere frontal, parietal, thalamic, and brainstem network plays an important role in the regulation of attention intensity, irrespective of stimulus modality. Under conditions of phasic alertness there is less right frontal activation reflecting a diminished need for top-down regulation with phasic extrinsic stimulation. Furthermore, a high overlap between the functional networks for alerting and spatial orienting of attention is demonstrated. These findings support the hypothesis of a co-activation of the posterior attention system involved in spatial orienting by the anterior alerting network. Possible implications of these findings for the therapy of neglect are proposed.


2009 ◽  
Vol 14 (1) ◽  
pp. 78-89 ◽  
Author(s):  
Kenneth Hugdahl ◽  
René Westerhausen

The present paper is based on a talk on hemispheric asymmetry given by Kenneth Hugdahl at the Xth European Congress of Psychology, Praha July 2007. Here, we propose that hemispheric asymmetry evolved because of a left hemisphere speech processing specialization. The evolution of speech and the need for air-based communication necessitated division of labor between the hemispheres in order to avoid having duplicate copies in both hemispheres that would increase processing redundancy. It is argued that the neuronal basis of this labor division is the structural asymmetry observed in the peri-Sylvian region in the posterior part of the temporal lobe, with a left larger than right planum temporale area. This is the only example where a structural, or anatomical, asymmetry matches a corresponding functional asymmetry. The increase in gray matter volume in the left planum temporale area corresponds to a functional asymmetry of speech processing, as indexed from both behavioral, dichotic listening, and functional neuroimaging studies. The functional anatomy of the corpus callosum also supports such a view, with regional specificity of information transfer between the hemispheres.


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